Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15326992 | 0.83 | HCRTR1 (0.69) | HCRTR1HCRTR2 | |
| SCHEMBL9977862 | 0.67 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL9977850 | 0.66 | HCRTR1 (0.79) | HCRTR1HCRTR2 | |
| SCHEMBL29839048 | 0.64 | CCR1 (0.50) | TGFBR1TGFBR2GRM5 | |
| SCHEMBL9977796 | 0.63 | HCRTR1 (0.74) | HCRTR1HCRTR2 | |
| SCHEMBL15338621 | 0.62 | HCRTR1 (0.58) | HCRTR1HCRTR2PDE10AAR | |
| SCHEMBL9977902 | 0.62 | HCRTR1 (0.72) | HCRTR1HCRTR2 | |
| SCHEMBL9977852 | 0.62 | CCR1 (0.50) | TGFBR1TGFBR2 | |
| SCHEMBL15604615 | 0.61 | HCRTR1 (0.50) | HCRTR1HCRTR2NAMPT | |
| SCHEMBL15604579 | 0.59 | HCRTR1 (0.49) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081692-A1 | PYRAZOLE DERIVATIVE | 大正製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |