Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 10/20 | 0.35 |
| ▸ | MAOA | P21397 | 8/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978115 | 1.00 | CA1 (0.41) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL9092847 | 1.00 | CA1 (0.41) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL9978232 | 0.78 | CHRM2 (0.41) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL9932176 | 0.77 | CHRM2 (0.35) | CHRM2CHRM1CHRM3 | |
| SCHEMBL3654981 | 0.77 | CHRM2 (0.35) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9931033 | 0.77 | CHRM2 (0.35) | CHRM2CHRM1CHRM3 | |
| SCHEMBL3751529 | 0.77 | CHRM2 (0.35) | CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9931863 | 0.75 | CHRM2 (0.34) | CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9931861 | 0.75 | CHRM2 (0.34) | CHRM2CHRM1CHRM3 | |
| SCHEMBL8744012 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |