Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 5/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410512 | 0.89 | MRGPRX4 (0.49) | CNR1CNR2CTSAPTGDR2MRGPRX4 | |
| SCHEMBL411012 | 0.88 | MRGPRX4 (0.52) | CNR1CNR2CTSAMRGPRX4MAPT | |
| SCHEMBL31267243 | 0.80 | CNR1 (0.45) | CNR1CNR2CTSAMAPTMEN1 | |
| SCHEMBL21634885 | 0.80 | CNR1 (0.45) | CNR1CNR2CTSAMAPTMEN1 | |
| SCHEMBL411488 | 0.80 | KDM4E (0.37) | CNR1CNR2PTGDR2MAPTKCNK3 | |
| SCHEMBL9935119 | 0.78 | CTSA (0.41) | CNR1CNR2CTSAMRGPRX4MAPT | |
| SCHEMBL9978011 | 0.77 | PTGDR2 (0.46) | CNR1CNR2PTGDR2MAPTMEN1 | |
| SCHEMBL21634717 | 0.76 | TTR (0.47) | MRGPRX4MAPTMEN1KMT2A | |
| SCHEMBL31267253 | 0.76 | TTR (0.47) | MRGPRX4MAPTMEN1KMT2A | |
| SCHEMBL21634704 | 0.75 | NOTUM (0.46) | CNR2CTSAMRGPRX4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |