Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 17/20 | 0.55 |
| ▸ | FLT3 | P36888 | 17/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.53 |
| ▸ | KIT | P10721 | 4/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.53 |
| ▸ | RET | P07949 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978911 | 0.96 | CSF1R (0.58) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL15388590 | 0.91 | FLT3 (0.66) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL15388552 | 0.91 | FLT3 (0.66) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL15388768 | 0.87 | FLT3 (0.54) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978680 | 0.87 | FLT3 (0.58) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL15388628 | 0.87 | FLT3 (0.70) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9980460 | 0.83 | CSF1R (0.60) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978908 | 0.83 | FLT3 (0.77) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978694 | 0.82 | FLT3 (0.59) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978652 | 0.82 | FLT3 (0.70) | CSF1RFLT3PDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | claimed |