SCHEMBL9979103

SCHEMBL9979103

O=C(CC(CC(=O)Nc1c(F)c(F)c(F)c(F)c1F)C(=O)Nc1c(F)c(F)c(F)c(F)c1F)Nc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TSHR P16473 4/20 0.42
ATM Q13315 1/20 0.36
POLB P06746 2/20 0.35
MAPK1 P28482 1/20 0.35
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
USP2 O75604 1/20 0.34
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
HTT P42858 2/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979349 0.84 GAA (0.48) GAAMEN1KMT2ATSHRATM
SCHEMBL3072029 0.75 GAA (0.61) GAAMEN1KMT2ATSHRATM
SCHEMBL4004138 0.70 GAA (0.55) GAAMEN1KMT2ATSHRATM
SCHEMBL3068709 0.68 GAA (0.53) GAAMEN1KMT2ATSHRATM
SCHEMBL15480437 0.68 MEN1 (0.67) GAAMEN1KMT2ATSHRATM
SCHEMBL22059758 0.65 NPSR1 (0.40) GAAMEN1KMT2ATSHRMAPK1
SCHEMBL22006513 0.65 GAA (0.50) GAAMEN1KMT2ATSHRATM
SCHEMBL21810569 0.65 GAA (0.55) GAAMEN1KMT2ATSHRMAPK1
SCHEMBL9615617 0.64 GAA (0.48) GAAMEN1KMT2ATSHRATM
SCHEMBL2089237 0.63 GAA (0.46) GAAMEN1KMT2ATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed