SCHEMBL9979280

SCHEMBL9979280

O=C(NC1CCCCCCCCC1)c1cc(C(=O)NC2CCCCCCCCC2)cc(C(=O)NC2CCCCCCCCC2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.69
MEN1 O00255 1/20 0.69
NPC1 O15118 9/20 0.65
RAB9A P51151 9/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
HPGD P15428 3/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C19 P33261 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.59
TP53 P04637 1/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
TAS1R3 Q7RTX0 2/20 0.58
TAS1R1 Q7RTX1 2/20 0.58
TAS1R2 Q8TE23 2/20 0.58
KDM4E B2RXH2 2/20 0.57
GFER P55789 1/20 0.57
HSD17B10 Q99714 1/20 0.57
HTR2B P41595 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2915946 1.00 KMT2A (0.69) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL2911740 1.00 KMT2A (0.69) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL435720 1.00 KMT2A (0.69) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL9978790 1.00 KMT2A (0.69) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL2908851 1.00 KMT2A (0.69) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL2695068 0.98 KMT2A (0.66) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL2911690 0.93 KMT2A (0.61) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL28429078 0.92 KMT2A (0.61) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL2229042 0.91 KMT2A (0.59) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL16622857 0.91 NPC1 (0.71) KMT2AMEN1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed