Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1339793 | 0.84 | KMT2A (0.46) | CA1CA2ACHEKMT2A | |
| SCHEMBL14392825 | 0.84 | KMT2A (0.46) | CA1CA2ACHEKMT2A | |
| SCHEMBL31278113 | 0.84 | KMT2A (0.46) | CA1CA2ACHEKMT2A | |
| SCHEMBL7221370 | 0.83 | CA12 (0.46) | CA1CA2KMT2AHSD11B1CA12 | |
| SCHEMBL20573432 | 0.83 | S1PR5 (0.45) | CA1CA2ACHEHSD11B1DRD2 | |
| SCHEMBL30967925 | 0.83 | KMT2A (0.44) | CA1CA2ACHEKMT2A | |
| SCHEMBL4013407 | 0.83 | KMT2A (0.44) | CA1CA2ACHEKMT2A | |
| SCHEMBL2071684 | 0.83 | KMT2A (0.44) | KMT2A | |
| SCHEMBL14231689 | 0.83 | KMT2A (0.44) | CA1CA2ACHEKMT2ADRD2 | |
| SCHEMBL4018322 | 0.83 | KMT2A (0.44) | CA1CA2ACHEKMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |