SCHEMBL9979519 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	FFAR1	O14842	3/20	0.43

▸	CD274	Q9NZQ7	2/20	0.39

▸	PPARD	Q03181	7/20	0.38

▸	PPARA	Q07869	3/20	0.37

▸	PPARG	P37231	2/20	0.37

▸	AOC3	Q16853	1/20	0.37

▸	SCN3A	Q9NY46	1/20	0.37

▸	CASP3	P42574	1/20	0.35

▸	CYP11B1	P15538	1/20	0.35

▸	CYP11B2	P19099	1/20	0.35

▸	PTGER4	P35408	1/20	0.35

▸	MEN1	O00255	1/20	0.35

▸	RAB9A	P51151	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9979690	0.95	PPARD (0.43)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979572	0.95	PPARD (0.43)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979705	0.92	PPARD (0.42)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979589	0.92	CYP11B1 (0.44)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979511	0.91	FFAR1 (0.52)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979512	0.89	PPARD (0.41)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979502	0.89	PPARD (0.41)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979507	0.87	PPARD (0.47)	FFAR1CD274PPARDPPARAPPARG
SCHEMBL9979638	0.87	PPARD (0.47)	FFAR1PPARDPPARAPPARGCYP11B1
SCHEMBL9979485	0.87	PPARD (0.47)	FFAR1PPARDPPARAPPARGCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012081570-A1	LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR	あすか製薬株式会社 (JP)	2012-06-21	—	—	WO	disclosed