SCHEMBL9979533 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	FFAR1	O14842	5/20	0.44

▸	PPARD	Q03181	10/20	0.40

▸	PPARA	Q07869	6/20	0.40

▸	PPARG	P37231	5/20	0.39

▸	FFAR4	Q5NUL3	1/20	0.37

▸	MRGPRX4	Q96LA9	1/20	0.36

▸	UGCG	Q16739	2/20	0.36

▸	S1PR1	P21453	3/20	0.34

▸	MCL1	Q07820	1/20	0.34

▸	PRKX	P51817	1/20	0.34

▸	IKBKE	Q14164	1/20	0.34

▸	S1PR5	Q9H228	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9979503	0.92	FFAR1 (0.44)	FFAR1PPARDPPARAPPARGFFAR4
SCHEMBL9979607	0.92	FFAR1 (0.39)	FFAR1PPARDPPARAPPARGMRGPRX4
SCHEMBL9979534	0.90	FFAR1 (0.49)	FFAR1PPARDPPARAPPARGFFAR4
SCHEMBL9979564	0.85	PPARD (0.59)	FFAR1PPARDPPARAPPARG
SCHEMBL9979641	0.85	PPARD (0.59)	FFAR1PPARDPPARAPPARG
SCHEMBL9979621	0.84	FFAR1 (0.52)	FFAR1PPARDPPARAPPARG
SCHEMBL9979523	0.84	FFAR1 (0.52)	FFAR1PPARDPPARAPPARG
SCHEMBL9979661	0.84	FFAR1 (0.52)	FFAR1PPARDPPARAPPARG
SCHEMBL9979505	0.84	FFAR1 (0.39)	FFAR1PPARDPPARAFFAR4MRGPRX4
SCHEMBL9979670	0.84	PPARD (0.53)	FFAR1PPARDPPARAPPARGS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012081570-A1	LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR	あすか製薬株式会社 (JP)	2012-06-21	—	—	WO	disclosed