Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852879 | 0.87 | MAPT (0.56) | MAPTTTRDPP4LMNAMDM2 | |
| SCHEMBL24611335 | 0.87 | MAPT (0.56) | MAPTTTRDPP4LMNAMDM2 | |
| SCHEMBL5640453 | 0.85 | TAAR1 (0.44) | MAPTTTRAKR1B10AKR1B1RAB9A | |
| SCHEMBL5640457 | 0.85 | TAAR1 (0.44) | MAPTTTRAKR1B10AKR1B1RAB9A | |
| SCHEMBL22877414 | 0.83 | MAPT (0.52) | MAPTTTRDPP4LMNAMDM2 | |
| SCHEMBL24611337 | 0.83 | MAPT (0.56) | MAPTLMNAMDM2ALDH1A1CYP4F2 | |
| SCHEMBL1268422 | 0.80 | MAPT (0.62) | MAPT | |
| SCHEMBL21678700 | 0.80 | MAPT (0.52) | MAPTTTRDPP4LMNAMDM2 | |
| SCHEMBL1268421 | 0.80 | MAPT (0.62) | MAPT | |
| SCHEMBL27310628 | 0.78 | MAPT (0.59) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |