Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.50 |
| ▸ | PPARA | Q07869 | 9/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | UGCG | Q16739 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979475 | 0.98 | PPARD (0.53) | PPARDPPARA | |
| SCHEMBL9979476 | 0.93 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL9979499 | 0.92 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL9979487 | 0.91 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL9979477 | 0.90 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL9979567 | 0.90 | PPARD (0.53) | PPARDPPARA | |
| SCHEMBL9979638 | 0.89 | PPARD (0.47) | PPARDPPARAPPARGUGCGCYP11B1 | |
| SCHEMBL9979485 | 0.89 | PPARD (0.47) | PPARDPPARAPPARGUGCGCYP11B1 | |
| SCHEMBL9979489 | 0.88 | PPARD (0.67) | PPARDPPARA | |
| SCHEMBL9979589 | 0.85 | CYP11B1 (0.44) | PPARDPPARAPPARGUGCGCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |