SCHEMBL9979631

SCHEMBL9979631

CCOC(=O)CC1CCc2cc(OCCCl)ccc21

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.64
PPARA Q07869 7/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979469 0.97 PPARD (0.65) PPARDPPARA
SCHEMBL12798817 0.91 PPARD (0.64) PPARDPPARA
SCHEMBL12798554 0.89 PPARD (0.64) PPARDPPARA
SCHEMBL12798841 0.89 PPARD (0.64) PPARDPPARA
SCHEMBL6251450 0.89 PPARD (0.64) PPARDPPARA
SCHEMBL6251448 0.89 PPARD (0.64) PPARDPPARA
SCHEMBL12798653 0.87 PPARD (0.68) PPARDPPARA
SCHEMBL12035617 0.85 PPARD (0.60) PPARDPPARA
SCHEMBL821099 0.85 PPARD (0.60) PPARDPPARA
SCHEMBL821443 0.85 PPARD (0.60) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012081570-A1 LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR あすか製薬株式会社 (JP) 2012-06-21 WO disclosed