Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979594 | 0.88 | POLB (0.61) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL3133285 | 0.85 | POLB (0.64) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL23117269 | 0.84 | POLB (0.56) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL32670275 | 0.84 | POLB (0.56) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL27064736 | 0.84 | POLB (0.57) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL29322261 | 0.84 | MAPT (0.69) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL9979457 | 0.83 | GAA (0.75) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL23116701 | 0.82 | TSHR (0.58) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL30708171 | 0.82 | POLB (0.56) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL25139597 | 0.82 | POLB (0.56) | POLBMEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |