Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480895 | 1.00 | USP5 (0.36) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL8517975 | 0.92 | ESR2 (0.35) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL14280896 | 0.88 | USP5 (0.33) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9476534 | 0.87 | USP5 (0.34) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9476554 | 0.87 | USP5 (0.34) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9476541 | 0.87 | USP5 (0.34) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9476548 | 0.87 | USP5 (0.34) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL9476544 | 0.87 | USP5 (0.34) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL18708399 | 0.86 | USP5 (0.35) | USP5HDAC6CCR2HTR2AHTR2C | |
| SCHEMBL13790844 | 0.86 | USP5 (0.35) | USP5HDAC6CCR2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168083-B2 | Electro-optical light control element, electro-optical display and control medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20100188630-A1 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-29 | — | — | US | disclosed |