⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998774 | 0.77 | — | — | |
| SCHEMBL1000509 | 0.74 | — | — | |
| SCHEMBL3468438 | 0.73 | — | — | |
| SCHEMBL10432545 | 0.72 | TSHR (0.52) | — | |
| SCHEMBL10432756 | 0.72 | TSHR (0.52) | — | |
| SCHEMBL18260100 | 0.72 | TSHR (0.52) | — | |
| SCHEMBL3818143 | 0.72 | TSHR (0.52) | — | |
| SCHEMBL139311 | 0.67 | — | — | |
| SCHEMBL16859971 | 0.65 | — | — | |
| SCHEMBL1192962 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422960-A2 | Rubber composition and crosslinkable rubber composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-04-17 | — | — | EP | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | disclosed |
| US-20240199553-A1 | DIFLUOROMETHYLATION REACTION OF HETEROCYCLIC RING USING TETRAFLUOROETHYLENE | AGC Inc. (JP) | 2024-06-20 | — | — | US | disclosed |
| EP-4385977-A1 | DIFLUOROMETHYLATION REACTION OF HETEROCYCLIC RING USING TETRAFLUOROETHYLENE | AGC INC. (JP) | 2024-06-19 | — | — | EP | disclosed |
| US-20240190885-A1 | KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX INC (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240190883-A1 | KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240182609-A1 | BRANCHED PROPYLENE-BASED POLYMER AND PRODUCTION METHOD THEREFOR | JAPAN POLYPROPYLENE CORPORATION (JP) | 2024-06-06 | — | — | US | disclosed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-0029998-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-06 | — | — | EP | disclosed |
| US-4493834-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0058779-B1 | CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | disclosed |
| US-4420477-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-12-13 | — | — | US | disclosed |
| EP-0095029-A1 | 5-Thio-tetrazol compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-30 | — | — | EP | disclosed |
| US-4396735-A | N-HETEROCYCLIC COMPOUND AND A HETEROCYCLIC ACID HYDRAZIDE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |
| US-4362831-A | A HINDERED AND HETEROCYCLIC AMINE WITH A THIOALKANOIC ACID AMIDE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |
| EP-0058779-A2 | Carboxamides, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1982-09-01 | — | — | EP | disclosed |
| EP-0029998-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-10 | — | — | EP | disclosed |
| US-4264461-A | PHOTOSTABILITY OF LUBRICANTS | ATLANTIC RICHFIELD COMPANY (US) | 1981-04-28 | — | — | US | disclosed |