Atrazine

Atrazine

SCHEMBL9983133

CCNc1nc(Cl)nc(NC(C)C)n1.CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.56
MAPT P10636 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.44
TSHR P16473 1/20 0.43
LMNA P02545 2/20 0.42
CYP3A4 P08684 1/20 0.41
PKM P14618 3/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dcmu SCHEMBL8736974 0.92 APEX1 (0.66) APEX1MAPTTSHRLMNACYP3A4
Fluometuron SCHEMBL9761347 0.82 TP53 (0.57) L3MBTL1LMNACYP3A4KMT2AMEN1
Atrazine SCHEMBL9876366 0.82 APEX1 (0.38) APEX1MAPTL3MBTL1TSHRLMNA
Propazine SCHEMBL9271309 0.81 CYP3A4 (0.66) MAPTL3MBTL1TSHRCYP3A4KMT2A
Propazine SCHEMBL9674230 0.81 CYP3A4 (0.66) MAPTL3MBTL1TSHRCYP3A4KMT2A
Dcmu SCHEMBL20723892 0.76 APEX1 (0.96) APEX1MAPTTSHRLMNACYP3A4
Dcmu SCHEMBL9576966 0.76 APEX1 (0.42) APEX1MAPTL3MBTL1TSHRLMNA
Dcmu SCHEMBL7279 0.75 APEX1 (1.00) APEX1MAPTTSHRLMNACYP3A4
Dcmu SCHEMBL29349863 0.75 APEX1 (1.00) APEX1MAPTTSHRLMNACYP3A4
Dcmu SCHEMBL1352353 0.75 APEX1 (1.00) APEX1MAPTTSHRLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8382982-B2 Apparatus merging wetland plants with a floating substrate to treat pollution in any river, lake or body of water HONDULAS JOHN L (US) 2013-02-26 US disclosed
US-20110297596-A1 Apparatus merging wetland plants with a floating substrate to treat pollution in any river, lake or body of water HONDULAS JOHN L (US) 2011-12-08 US disclosed
US-4249938-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-02-10 US disclosed