Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13082566 | 0.83 | AR (0.37) | L3MBTL1ALDH1A1HPGDKDM4EAR | |
| SCHEMBL7215618 | 0.82 | HPGD (0.42) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27781329 | 0.77 | HPGD (0.41) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL7219978 | 0.77 | HPGD (0.56) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL21883774 | 0.76 | HSD17B10 (0.40) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL19880572 | 0.75 | KDM4E (0.41) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL21883663 | 0.75 | TSHR (0.39) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL10376318 | 0.73 | HPGD (0.38) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL3313973 | 0.72 | HPGD (0.51) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL7213741 | 0.72 | HPGD (0.40) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157339-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-12-22 | — | — | WO | disclosed |