Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.35 |
| ▸ | CDC25B | P30305 | 8/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 6/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 5/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14841708 | 1.00 | BCHE (0.37) | BCHESLC5A2NT5EPTPN1CDC25B | |
| SCHEMBL2131750 | 0.85 | BCHE (0.41) | BCHESLC5A2NT5EPTPN1CDC25B | |
| SCHEMBL2129610 | 0.82 | NT5E (0.42) | BCHENT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL2133682 | 0.81 | PTPN1 (0.43) | BCHESLC5A2NT5EPTPN1CDC25B | |
| SCHEMBL9984091 | 0.80 | SLC5A2 (0.45) | BCHESLC5A2NT5EPTPN1CDC25B | |
| SCHEMBL2130169 | 0.80 | BCHE (0.43) | BCHESLC5A2NT5EPTPN1CDC25B | |
| Hydrochloric Acid SCHEMBL9984358 | 0.77 | PTPN1 (0.41) | BCHESLC5A2NT5EPTPN1CDC25B | |
| SCHEMBL2130715 | 0.77 | PTPN1 (0.39) | BCHESLC5A2NT5EPTPN1CDC25B | |
| SCHEMBL15610890 | 0.77 | PTPN1 (0.43) | BCHESLC5A2NT5EPTPN1CDC25B | |
| SCHEMBL2131297 | 0.77 | PTPN1 (0.43) | BCHESLC5A2NT5EPTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159067-A2 | THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2011-12-22 | — | — | WO | disclosed |