Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 6/20 | 0.70 |
| ▸ | ELANE | P08246 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 3/20 | 0.54 |
| ▸ | KLK14 | Q9P0G3 | 3/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.54 |
| ▸ | CTSG | P08311 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257723 | 0.91 | C1R (0.58) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL9985296 | 0.88 | ELANE (0.64) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL25054223 | 0.88 | C1R (0.63) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL9984176 | 0.88 | ELANE (0.64) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL9985005 | 0.88 | ELANE (0.64) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL9984385 | 0.85 | ELANE (0.66) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL5921483 | 0.83 | ELANE (0.51) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL5780185 | 0.83 | C1R (1.00) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL914419 | 0.76 | C1R (0.70) | C1RELANEKMT2AMEN1MAPT | |
| SCHEMBL4116511 | 0.76 | ELANE (0.70) | C1RELANEKMT2AMEN1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319611-A1 | BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CHANG GUNG UNIVERSITY (TW) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319611-A1 | BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CYP4X1, CYP2B6, CYP2C19 | C1R 84/4885ELANE 3461/4885KMT2A 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.