Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984809 | 1.00 | KCNH2 (0.38) | KCNH2ROCK2MTNR1AMTNR1B | |
| SCHEMBL9985505 | 1.00 | KCNH2 (0.38) | KCNH2ROCK2MTNR1AMTNR1B | |
| SCHEMBL9985509 | 1.00 | KCNH2 (0.38) | KCNH2ROCK2MTNR1AMTNR1B | |
| SCHEMBL9985643 | 1.00 | KCNH2 (0.38) | KCNH2ROCK2MTNR1AMTNR1B | |
| SCHEMBL9984811 | 1.00 | KCNH2 (0.38) | KCNH2ROCK2MTNR1AMTNR1B | |
| SCHEMBL9986536 | 0.93 | IDO1 (0.31) | KCNH2 | |
| SCHEMBL9987478 | 0.93 | IDO1 (0.31) | KCNH2 | |
| SCHEMBL9987476 | 0.93 | IDO1 (0.31) | KCNH2 | |
| SCHEMBL9986537 | 0.93 | IDO1 (0.31) | KCNH2 | |
| SCHEMBL9985767 | 0.90 | KCNH2 (0.35) | KCNH2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040321-A3 | METHODS AND APPARATUS FOR EHNANCED GAS DISTRIBUTION | GRUPO PETROTEMEX, S.A. DE C.V. (MX) | 2012-05-10 | — | — | WO | claimed |
| EP-1981881-B1 | TETRAHYDROPYRANE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-12-07 | — | — | EP | claimed |
| WO-2012040321-A3 | METHODS AND APPARATUS FOR EHNANCED GAS DISTRIBUTION | GRUPO PETROTEMEX, S.A. DE C.V. (MX) | 2012-05-10 | — | — | WO | disclosed |
| EP-1981881-B1 | TETRAHYDROPYRANE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-12-07 | — | — | EP | disclosed |