Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711228 | 1.00 | PPM1D (0.38) | PPM1DCNR2 | |
| SCHEMBL660447 | 1.00 | PPM1D (0.38) | PPM1DCNR2 | |
| SCHEMBL5711230 | 1.00 | PPM1D (0.38) | PPM1DCNR2 | |
| SCHEMBL25382185 | 0.96 | PPM1D (0.35) | PPM1D | |
| SCHEMBL661089 | 0.89 | PPM1D (0.34) | PPM1D | |
| SCHEMBL5831542 | 0.89 | PPM1D (0.34) | PPM1D | |
| SCHEMBL20758481 | 0.89 | PPM1D (0.34) | PPM1D | |
| SCHEMBL360950 | 0.89 | PPM1D (0.36) | PPM1D | |
| SCHEMBL1015667 | 0.89 | PPM1D (0.34) | PPM1D | |
| SCHEMBL18535817 | 0.89 | PPM1D (0.34) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585444-A1 | AZASPIROHEXANONES AS INHIBITORS OF 11-BETA-HSD1 FOR THE TREATMENT OF METABOLIC DISORDERS | Boehringer Ingelheim International GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011161128-A1 | AZASPIROHEXANONES AS INHIBITORS OF 11-BETA-HSD1 FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |
| EP-1773791-B1 | PYRROLOTRIAZINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2010-09-22 | — | — | EP | disclosed |