[2,3'']Bipyridinyl

[2,3'']Bipyridinyl

SCHEMBL998601

c1ccc(-c2cccnc2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 9/20 1.00
TP53 P04637 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
PKM P14618 1/20 0.60
TSHR P16473 1/20 0.60
CYP3A4 P08684 2/20 0.58
CYP1A2 P05177 2/20 0.58
ALDH1A1 P00352 2/20 0.58
PIM1 P11309 1/20 0.56
PIM2 Q9P1W9 1/20 0.56
CYP19A1 P11511 2/20 0.55
KDM4E B2RXH2 2/20 0.54
LMNA P02545 2/20 0.54
POLB P06746 1/20 0.54
CCR1 P32246 1/20 0.54
CCR5 P51681 1/20 0.54
CCR8 P51685 1/20 0.54
METAP1 P53582 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
[2,3'']Bipyridinyl SCHEMBL29389597 1.00 CYP2A6 (1.00) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL29360744 1.00 CYP2A6 (1.00) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL29486847 1.00 CYP2A6 (1.00) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL1418333 0.98 CYP2A6 (0.96) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL29156067 0.96 CYP2A6 (0.92) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL29050665 0.94 CYP2A6 (0.89) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL29189545 0.94 CYP2A6 (0.89) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL29050656 0.94 CYP2A6 (0.89) CYP2A6TP53SMN1; SMN2NPC1RAB9A
[2,3'']Bipyridinyl SCHEMBL29189475 0.94 CYP2A6 (0.89) CYP2A6TP53SMN1; SMN2NPC1RAB9A
SCHEMBL3509967 0.92 CYP2A6 (0.85) CYP2A6TP53SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1037 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388543-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-25 US claimed
WO-2025060259-A1 BLACK PHOSPHORUS-CARBON-NITROGEN COMPOSITE NEGATIVE ELECTRODE MATERIAL AND PREPARATION METHOD THEREFOR 中国科学院深圳先进技术研究院 2025-03-27 WO claimed
CN-119355159-A Detection method of ten tobacco alkaloids in soil 云南农业大学 2025-01-24 CN claimed
CN-119307185-A Chemical mechanical polishing composition suitable for planarization of silicon-based devices and application thereof 万华化学集团电子材料有限公司 2025-01-14 CN claimed
US-12162813-B2 Process for preparing 3,3,3-trifluoroprop-1-ene THE CHEMOURS COMPANY FC, LLC (US) 2024-12-10 US claimed
CN-118988222-A System and process for dehydrochlorination of chlorinated alkane 西安近代化学研究所 2024-11-22 CN claimed
CN-118988406-A Homogeneous catalyst for preparing chlorinated alkene by dehydrochlorination of chlorinated alkane 西安近代化学研究所 2024-11-22 CN claimed
CN-112533904-B Melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof 克林提克斯医药股份有限公司 2024-10-29 CN claimed
CN-118731225-A Method for measuring content of pirenzepine intermediate 海南葫芦娃药业集团股份有限公司 2024-10-01 CN claimed
CN-114460209-B Method for measuring seven alkaloid contents in fresh tobacco leaves 云南中烟工业有限责任公司 2024-09-24 CN claimed
EP-0315149-B1 PROCESS FOR THE PREPARATION OF IMIDIZED ACRYLIC POLYMERS ELF ATOCHEM ITALIA S.r.l. (IT) 1993-09-01 EP claimed
EP-0371095-B1 PROCEDURE FOR PRODUCING ALCOHOLS AND ALDEHYDES FROM ALKENES AND SYNTHESIS GASES NESTE OY (FI) 1993-07-28 EP claimed
US-5208278-A STABILIZED POLYARYL ETHER KETONE MOLDING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1993-05-04 US claimed
EP-0275918-B1 PROCESS FOR THE PREPARATION OF IMIDIZED ACRYLIC POLYMERS ATOCHEM INDUSTRIALE s.r.l. (IT) 1992-03-25 EP claimed
EP-0451556-A2 Stabilised polyaryletherketone - moulding compounds BASF Aktiengesellschaft (DE) 1991-10-16 EP claimed
US-5021514-A Imidized acrylic polymers and process for their preparation VEDRIL S.P.A. (IT) 1991-06-04 US claimed
EP-0315149-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-05-10 EP claimed
EP-0315150-A2 Imidized acrylic polymers and process for the preparation thereof ELF ATOCHEM ITALIA S.r.l. (IT) 1989-05-10 EP claimed
US-4061638-A Organocalciumpyridine-type polymerization initiators PHILLIPS PETROLEUM COMPANY (US) 1977-12-06 US claimed
US-3997708-A ADDITION PHILLIPS PETROLEUM COMPANY (US) 1976-12-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388543-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN SCN8A, SCN1B, SCN3A CYP2A6 412/4885TP53 4778/4885SMN1; SMN2 738/4885
US-12162813-B2 Process for preparing 3,3,3-trifluoroprop-1-ene SULT1E1, FIP1L1, GTF3C3 CYP2A6 872/4885TP53 3693/4885SMN1; SMN2 1469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.