Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 20/20 | 0.57 |
| ▸ | BRAF | P15056 | 14/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986375 | 0.85 | TNNI3K (0.57) | TNNI3KBRAFEGFR | |
| SCHEMBL9985681 | 0.83 | TNNI3K (0.56) | TNNI3KBRAFEGFR | |
| SCHEMBL9985458 | 0.83 | TNNI3K (0.59) | TNNI3KBRAFEGFR | |
| SCHEMBL9985782 | 0.80 | TNNI3K (0.58) | TNNI3KBRAFEGFR | |
| SCHEMBL9986750 | 0.80 | TNNI3K (0.59) | TNNI3KBRAFEGFR | |
| SCHEMBL9978331 | 0.80 | TNNI3K (0.49) | TNNI3KBRAFEGFR | |
| SCHEMBL9986107 | 0.79 | TNNI3K (0.48) | TNNI3KBRAFEGFR | |
| SCHEMBL9985228 | 0.77 | TNNI3K (0.57) | TNNI3KBRAFEGFR | |
| SCHEMBL9985434 | 0.77 | TNNI3K (0.47) | TNNI3KBRAFEGFR | |
| SCHEMBL9985639 | 0.76 | TNNI3K (0.59) | TNNI3KBRAFEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | claimed |
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |