Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 20/20 | 0.49 |
| ▸ | BRAF | P15056 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986399 | 0.81 | TNNI3K (0.56) | TNNI3KBRAF | |
| SCHEMBL9985530 | 0.79 | TNNI3K (0.61) | TNNI3KBRAF | |
| SCHEMBL9985526 | 0.79 | TNNI3K (0.56) | TNNI3KBRAF | |
| SCHEMBL9985326 | 0.79 | TNNI3K (0.56) | TNNI3KBRAF | |
| SCHEMBL12067092 | 0.77 | TNNI3K (0.81) | TNNI3KBRAF | |
| SCHEMBL9986060 | 0.76 | TNNI3K (0.64) | TNNI3KBRAF | |
| SCHEMBL9985758 | 0.74 | TNNI3K (0.61) | TNNI3KBRAF | |
| SCHEMBL9985768 | 0.73 | TNNI3K (0.48) | TNNI3KBRAF | |
| SCHEMBL9985458 | 0.73 | TNNI3K (0.59) | TNNI3KBRAF | |
| SCHEMBL9986121 | 0.72 | TNNI3K (0.52) | TNNI3KBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | claimed |
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |