Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 16/20 | 0.62 |
| ▸ | BRAF | P15056 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985412 | 0.89 | TNNI3K (0.56) | TNNI3KBRAFKDM4EALDH1A1MAPT | |
| SCHEMBL9985438 | 0.84 | TNNI3K (0.64) | TNNI3KBRAFKDM4EALDH1A1MAPT | |
| SCHEMBL12067174 | 0.79 | TNNI3K (0.73) | TNNI3KBRAF | |
| SCHEMBL12067134 | 0.77 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12066418 | 0.77 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12067143 | 0.77 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL9987032 | 0.76 | TNNI3K (0.64) | TNNI3KBRAFKDM4EALDH1A1MAPT | |
| SCHEMBL12067184 | 0.75 | TNNI3K (0.72) | TNNI3KBRAF | |
| SCHEMBL12065601 | 0.73 | TNNI3K (0.69) | TNNI3KBRAFKDM4EALDH1A1MAPT | |
| SCHEMBL14321934 | 0.72 | TNNI3K (0.80) | TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | claimed |