Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 20/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986752 | 1.00 | SLC5A2 (0.80) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL14841922 | 1.00 | SLC5A2 (0.80) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL9984067 | 0.93 | SLC5A2 (0.79) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL14841703 | 0.92 | SLC5A2 (0.80) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL9984307 | 0.92 | SLC5A2 (0.76) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL14840934 | 0.89 | SLC5A2 (1.00) | SLC5A2 | |
| SCHEMBL9986935 | 0.89 | SLC5A2 (1.00) | SLC5A2 | |
| SCHEMBL9986942 | 0.89 | SLC5A2 (1.00) | SLC5A2 | |
| SCHEMBL9984256 | 0.89 | SLC5A2 (0.80) | SLC5A2 | |
| SCHEMBL14841751 | 0.88 | SLC5A2 (0.80) | SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159067-A2 | THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2011-12-22 | — | — | WO | claimed |
| WO-2011159067-A2 | THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2011-12-22 | — | — | WO | disclosed |