Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986795 | 0.93 | BRAF (0.74) | BRAF | |
| SCHEMBL9986793 | 0.93 | BRAF (0.74) | BRAF | |
| SCHEMBL14858927 | 0.90 | BRAF (0.54) | BRAF | |
| SCHEMBL9987267 | 0.89 | BRAF (0.65) | BRAF | |
| SCHEMBL9987568 | 0.88 | BRAF (0.53) | BRAF | |
| SCHEMBL9988265 | 0.87 | BRAF (0.63) | BRAF | |
| SCHEMBL14858925 | 0.87 | BRAF (0.56) | BRAF | |
| SCHEMBL14866063 | 0.86 | BRAF (0.73) | BRAF | |
| SCHEMBL9987114 | 0.85 | BRAF (0.68) | BRAF | |
| SCHEMBL9987115 | 0.85 | BRAF (0.68) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585454-A1 | HETEROARYL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | Novartis AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011161216-A1 | HETEROARYL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2011-12-29 | — | — | WO | disclosed |