Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987727 | 0.88 | GCK (0.73) | GCK | |
| SCHEMBL9986994 | 0.86 | GCK (1.00) | GCK | |
| SCHEMBL9986909 | 0.86 | GCK (1.00) | GCK | |
| SCHEMBL9987128 | 0.86 | GCK (0.81) | GCK | |
| SCHEMBL12071832 | 0.85 | GCK (0.80) | GCK | |
| SCHEMBL9986997 | 0.85 | GCK (1.00) | GCK | |
| SCHEMBL9986665 | 0.85 | GCK (0.85) | GCK | |
| SCHEMBL9987431 | 0.84 | GCK (1.00) | GCK | |
| SCHEMBL9987116 | 0.84 | GCK (1.00) | GCK | |
| SCHEMBL9987532 | 0.83 | GCK (1.00) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011158149-A1 | 2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES | PFIZER INC. (US) | 2011-12-22 | — | — | WO | disclosed |