Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 19/20 | 0.49 |
| ▸ | BRAF | P15056 | 15/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978322 | 0.88 | TNNI3K (0.63) | TNNI3KBRAF | |
| SCHEMBL9986916 | 0.88 | TNNI3K (0.59) | TNNI3KBRAF | |
| SCHEMBL9978244 | 0.88 | TNNI3K (0.55) | TNNI3KBRAF | |
| SCHEMBL9978327 | 0.86 | TNNI3K (0.51) | TNNI3KBRAF | |
| SCHEMBL9985725 | 0.80 | TNNI3K (0.57) | TNNI3KBRAF | |
| SCHEMBL9985228 | 0.80 | TNNI3K (0.57) | TNNI3KBRAF | |
| SCHEMBL9985782 | 0.79 | TNNI3K (0.58) | TNNI3KBRAF | |
| SCHEMBL9985639 | 0.79 | TNNI3K (0.59) | TNNI3KBRAF | |
| SCHEMBL9986007 | 0.79 | TNNI3K (0.60) | TNNI3KBRAF | |
| SCHEMBL12067084 | 0.78 | TNNI3K (0.79) | TNNI3KBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |