Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987434 | 1.00 | GCK (0.63) | GCK | |
| SCHEMBL9987903 | 0.93 | GCK (0.63) | GCK | |
| SCHEMBL9987897 | 0.93 | GCK (0.63) | GCK | |
| SCHEMBL9987321 | 0.86 | GCK (0.84) | GCK | |
| SCHEMBL9987306 | 0.86 | GCK (0.84) | GCK | |
| SCHEMBL9987394 | 0.85 | GCK (0.82) | GCK | |
| SCHEMBL9987400 | 0.85 | GCK (0.82) | GCK | |
| SCHEMBL9987098 | 0.81 | GCK (0.63) | GCK | |
| SCHEMBL9987102 | 0.81 | GCK (0.63) | GCK | |
| SCHEMBL2085473 | 0.80 | GCK (0.56) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011158149-A1 | 2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES | PFIZER INC. (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011158149-A1 | 2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES | PFIZER INC. (US) | 2011-12-22 | — | — | WO | disclosed |