Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945130 | 1.00 | ACACB (0.45) | ACACBPARP15PARP10PARP2ACACA | |
| Hydrochloric Acid SCHEMBL2139079 | 0.98 | ACACB (0.44) | ACACBPARP15PARP10PARP2ACACA | |
| SCHEMBL13727971 | 0.87 | ACACB (0.46) | ACACBPARP15PARP10PARP2ACACA | |
| SCHEMBL29457133 | 0.81 | PARP15 (0.51) | ACACBPARP15PARP10PARP2ACACA | |
| SCHEMBL31681100 | 0.80 | ACACB (0.44) | ACACBPARP15PARP10PARP2ACACA | |
| SCHEMBL21921012 | 0.78 | ACACB (0.40) | ACACBACACA | |
| SCHEMBL17246825 | 0.77 | PARP15 (0.51) | ACACBPARP15PARP10PARP2ACACA | |
| SCHEMBL19876587 | 0.77 | PARP15 (0.51) | ACACBPARP15PARP10PARP2ACACA | |
| SCHEMBL7601081 | 0.77 | PARP15 (0.51) | ACACBPARP15PARP10PARP2ACACA | |
| SCHEMBL31355010 | 0.76 | CYP4F2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966156-B1 | NEW COMPOUNDS III | ASTRAZENECA AB (SE) | 2011-12-21 | — | — | EP | disclosed |