Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14093813 | 0.98 | FFAR4 (0.57) | FFAR4FFAR1LMNATSHRNFKB1 | |
| SCHEMBL559468 | 0.98 | FFAR4 (0.57) | FFAR4FFAR1LMNATSHRNFKB1 | |
| SCHEMBL304217 | 0.98 | FFAR4 (0.57) | FFAR4FFAR1LMNATSHRNFKB1 | |
| SCHEMBL2348647 | 0.93 | CYP1A2 (0.50) | FFAR4FFAR1LMNACYP1A2TSHR | |
| SCHEMBL10068076 | 0.93 | CYP1A2 (0.50) | FFAR4FFAR1LMNACYP1A2TSHR | |
| SCHEMBL28041784 | 0.92 | FFAR4 (0.52) | FFAR4FFAR1LMNATSHRNFKB1 | |
| SCHEMBL12153331 | 0.85 | CA1 (0.48) | CYP1A2ALDH1A1LTA4HTDP1 | |
| SCHEMBL233498 | 0.84 | CYP1A2 (0.70) | FFAR4FFAR1LMNACYP1A2TSHR | |
| SCHEMBL15933413 | 0.84 | PAOX (0.44) | FFAR4FFAR1LMNACYP1A2ALDH1A1 | |
| SCHEMBL25923088 | 0.84 | CYP1A2 (0.70) | FFAR4FFAR1LMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165544-A | Pentamethine cyanine dye fluorescent probe synthesis and application suitable for dynamic super-resolution imaging of cell membranes | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | claimed |
| CN-118165544-A | Pentamethine cyanine dye fluorescent probe synthesis and application suitable for dynamic super-resolution imaging of cell membranes | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | disclosed |
| EP-1874871-B1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LTD (GB) | 2012-10-03 | — | — | EP | disclosed |
| EP-2270106-A2 | Indolium compounds containing fluoro-substituents | GE Healthcare UK Limited (GB) | 2011-01-05 | — | — | EP | disclosed |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2010-09-30 | — | — | US | disclosed |
| US-7767829-B2 | Water-soluble fluoro-substituted cyanine dyes as reactive fluorescence labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2010-08-03 | — | — | US | disclosed |
| EP-2157088-A1 | INDICYANINE DYES AND THE DERIVATIVES THEREOF FOR ANALYSING BIOLOGICAL MICROMOLECULES | UCHREZHDENIE ROSSIISKOI AKADEMII NAUK INSTITUT MOLEKULYARNOI BIOLOGII IM. V.A. ENGELGARDTA RAN (IMB RAN) (RU) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008127139-A1 | INDICYANINE DYES AND THE DERIVATIVES THEREOF FOR ANALYSING BIOLOGICAL MICROMOLECULES | INSTITUT MOLEKULYARNOI BIOLOGII IM. V.A. ENGELDARDTA ROSSIISKOI AKADEMII NAUK (RU) | 2008-10-23 | — | — | WO | disclosed |
| EP-1874871-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE Healthcare UK Limited (GB) | 2008-01-09 | — | — | EP | disclosed |
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | US | disclosed |
| WO-2006111726-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | TPD52L2, MRPL21, MRPL9 | FFAR4 234/4885FFAR1 436/4885LMNA 2637/4885 |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | TPD52L2, MRPL9, MRPL21 | FFAR4 232/4885FFAR1 428/4885LMNA 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.