SCHEMBL9995405

SCHEMBL9995405

CN(C)CCC(Oc1cccc2ccccc12)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 13/20 0.67
SLC6A2 P23975 11/20 0.67
HTR1B P28222 3/20 0.54
HRH3 Q9Y5N1 1/20 0.51
CACNA2D1 P54289 1/20 0.50
UTS2R Q9UKP6 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6726247 0.99 SLC6A4 (0.65) SLC6A4SLC6A2HTR1BHRH3CACNA2D1
Maleic Acid SCHEMBL7311827 0.90 SLC6A2 (0.56) SLC6A4SLC6A2HTR1BUTS2R
SCHEMBL25670014 0.88 SLC6A4 (0.62) SLC6A4SLC6A2HTR1B
SCHEMBL5080333 0.86 CACNA2D1 (0.57) SLC6A4SLC6A2HTR1BCACNA2D1
Iodide SCHEMBL2607 0.85 CACNA2D1 (0.56) SLC6A4SLC6A2HTR1BCACNA2D1
SCHEMBL3458 0.84 SLC6A2 (0.71) SLC6A4SLC6A2HTR1BCACNA2D1
Oxalic Acid SCHEMBL3521 0.83 CACNA2D1 (0.52) SLC6A4SLC6A2HTR1BCACNA2D1UTS2R
SCHEMBL8026016 0.83 SLC6A4 (0.51) SLC6A4SLC6A2HRH3UTS2R
SCHEMBL8285421 0.82 SLC6A4 (0.69) SLC6A4SLC6A2
Oxalic Acid SCHEMBL3562 0.81 SLC6A2 (0.63) SLC6A4SLC6A2HTR1BCACNA2D1UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011161690-A1 PROCESSES FOR THE PREPARATION OF (+)-N,N-DIMETHYL-2-[1-(NAPHTHALENYLOXY) ETHYL] BENZENE METHANAMINE AND INTERMEDIATES THEREOF SYMED LABS LIMITED (IN) 2011-12-29 WO disclosed