Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.67 |
| ▸ | CASP6 | P55212 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15056016 | 0.87 | SMN1; SMN2 (0.70) | PKMMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1130086 | 0.86 | MCL1 (0.68) | MCL1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL9997330 | 0.85 | MCL1 (0.70) | MCL1MEN1KMT2AGAAGFER | |
| SCHEMBL7828166 | 0.84 | MCL1 (0.78) | APAF1CASP6TDP1L3MBTL1MCL1 | |
| SCHEMBL11888673 | 0.84 | MEN1 (0.61) | CASP6L3MBTL1PKMMEN1KMT2A | |
| SCHEMBL150434 | 0.83 | MCL1 (0.68) | MCL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL9997075 | 0.83 | MCL1 (0.68) | MCL1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9997160 | 0.83 | HSD17B10 (0.70) | MCL1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9997129 | 0.83 | PFKFB3 (0.62) | APAF1CASP6TDP1L3MBTL1MCL1 | |
| SCHEMBL15055864 | 0.83 | SMN1; SMN2 (0.69) | PKMLMNASMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794009-B1 | BISARYLSULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2017-08-30 | — | — | EP | claimed |
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |