SCHEMBL9999552

SCHEMBL9999552

COc1ccc(C(C)(C)c2ccc(OC(=O)CCCCC(C)=O)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.47
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 3/20 0.47
LMNA P02545 5/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 3/20 0.46
HTT P42858 1/20 0.46
EGFR P00533 2/20 0.46
ERBB2 P04626 2/20 0.46
GAA P10253 2/20 0.42
ALOX15 P16050 1/20 0.42
APEX1 P27695 1/20 0.42
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12346026 0.99 KMT2A (0.46) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL9999550 0.99 KMT2A (0.46) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL12346029 0.99 KMT2A (0.46) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL15001296 0.99 KMT2A (0.46) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL12346024 0.99 KMT2A (0.46) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL15001298 0.97 EGFR (0.49) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL15143828 0.90 KMT2A (0.46) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL12345954 0.88 KMT2A (0.44) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL17955525 0.87 MAPT (0.48) KMT2AHSD17B10MEN1LMNAMAPT
SCHEMBL16093179 0.85 KMT2A (0.53) KMT2AHSD17B10MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 US disclosed
US-9404001-B2 Photochromic latex ink XEROX CORPORATION (US) 2016-08-02 US disclosed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 US disclosed
US-9091949-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-07-28 US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-20150177629-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION 2015-06-25 US disclosed
US-20150153479-A1 PHOTOCHROMIC LATEX INK XEROX CORPORATION (US) 2015-06-04 US disclosed
US-9046798-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-06-02 US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 US disclosed
US-20150050587-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION (US) 2015-02-19 US disclosed
US-20140087297-A1 LOW STRAIN ANTI-CURL BACK COATING FOR FLEXIBLE IMAGING MEMBERS XEROX CORPORATION (US) 2014-03-27 US disclosed
US-8465887-B2 Lower cost reusable polymer binder XEROX CORPORATION (US) 2013-06-18 US disclosed
US-20130143016-A1 ALTERNATE ANTICURL BACK COATING FORMULATION XEROX CORPORATION (US) 2013-06-06 US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 US disclosed
US-8303858-B2 Photochromic polymer with binder XEROX CORPORATION (US) 2012-11-06 US disclosed
US-8287963-B2 Erasable medium with uncoated substrate XEROX CORPORATION (US) 2012-10-16 US disclosed
US-20120040199-A1 ERASABLE MEDIUM WITH UNCOATED SUBSTRATE XEROX CORPORATION (US) 2012-02-16 US disclosed
US-20110281482-A1 NOVEL LOWER COST REUSABLE POLYMER BINDER XEROX CORPORATION (US) 2011-11-17 US disclosed
US-20110215283-A1 PHOTOCHROMIC POLYMER WITH BINDER XEROX CORPORATION (US) 2011-09-08 US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 US disclosed