SCHEMBL9999690

SCHEMBL9999690

NCCSc1cc(C(F)(F)F)nc2c(F)cccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KIF11 P52732 2/20 0.34
PRKD3 O94806 1/20 0.33
MAP4K4 O95819 1/20 0.33
CDK1 P06493 1/20 0.33
CSF1R P07333 1/20 0.33
PIM1 P11309 1/20 0.33
CDK2 P24941 1/20 0.33
MARK3 P27448 1/20 0.33
AKT1 P31749 1/20 0.33
FLT4 P35916 1/20 0.33
FLT3 P36888 1/20 0.33
FRK P42685 1/20 0.33
MAPKAPK2 P49137 1/20 0.33
CLK2 P49760 1/20 0.33
RPS6KA3 P51812 1/20 0.33
MAPK12 P53778 1/20 0.33
CSNK2A1 P68400 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999683 0.86 MAPT (0.42) MAPTMEN1KMT2AMAP4K4CSNK2A1
SCHEMBL9999685 0.80 MAPT (0.64) MAPTMEN1KMT2AKIF11PKM
SCHEMBL6354888 0.76 KDM4E (0.38) MAPTMEN1KMT2APRKD3MAP4K4
SCHEMBL2711028 0.74 NT5E (0.49) MAPTMEN1KMT2APRKD3MAP4K4
SCHEMBL2709776 0.73 PRKD3 (0.40) PRKD3MAP4K4CDK1CSF1RPIM1
SCHEMBL19584236 0.72 NT5E (0.36) MEN1KMT2APRKD3MAP4K4CDK1
SCHEMBL9999693 0.71 MAPT (0.48) MAPTMEN1KMT2AKIF11KDM4E
SCHEMBL19148554 0.71 KCNH2 (0.42) PRKD3MAP4K4CDK1CSF1RPIM1
SCHEMBL26406769 0.70 SRPK1 (0.43) MAPTMEN1KMT2APRKD3MAP4K4
SCHEMBL11669235 0.69 AURKA (0.55) PRKD3MAP4K4CDK1CSF1RPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018025872-A1 LIQUID CRYSTAL DISPLAY ELEMENT EQUIPPED WITH LIQUID CRYSTAL PANEL HAVING CURVED SURFACE AND LIQUID CRYSTAL ALIGNING AGENT FOR SAME 日産化学工業株式会社 2018-02-08 WO disclosed
WO-2012014898-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学工業株式会社 (JP) 2012-02-02 WO disclosed