Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979797 | 1.00 | CYP1A2 (0.34) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL13464035 | 1.00 | CYP1A2 (0.34) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL13463951 | 0.95 | CYP1A2 (0.39) | CYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9979801 | 0.95 | CYP1A2 (0.39) | CYP1A2HTTLMNAMAPK1 | |
| SCHEMBL13463953 | 0.95 | CYP1A2 (0.37) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL13464034 | 0.94 | CYP1A2 (0.40) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL9999744 | 0.92 | CYP1A2 (0.35) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL13464012 | 0.92 | CYP1A2 (0.35) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL13463952 | 0.92 | CYP1A2 (0.35) | CYP1A2PKMHTTMEN1KMT2A | |
| SCHEMBL13464015 | 0.91 | CYP1A2 (0.42) | CYP1A2HTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703013-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2014-04-22 | — | — | US | disclosed |
| US-20130187092-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-07-25 | — | — | US | disclosed |
| US-20130037745-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-02-14 | — | — | US | disclosed |
| US-20120161073-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-06-28 | — | — | US | disclosed |