SCHEMBL9999838

SCHEMBL9999838

CC(=O)c1ccc(Oc2ccc(Oc3ccc(C)cc3)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.83
HPGD P15428 3/20 0.83
RAB9A P51151 2/20 0.83
MMP13 P45452 2/20 0.63
MAOB P27338 1/20 0.62
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 1/20 0.59
MAPK1 P28482 1/20 0.59
STAT3 P40763 1/20 0.59
STAT1 P42224 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
LMNA P02545 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
ESRRA P11474 1/20 0.53
GAA P10253 1/20 0.52
ALDH1A1 P00352 3/20 0.50
KMT2A Q03164 1/20 0.50
PARP15 Q460N3 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL903435 1.00 MAPT (0.83) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL10014131 0.94 HPGD (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL10014134 0.94 MAPT (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL16995927 0.94 HPGD (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL12062003 0.94 HPGD (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL24380498 0.94 MAPT (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL9999840 0.94 HPGD (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL21935265 0.94 MAPT (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL22929838 0.94 MAPT (0.73) MAPTHPGDRAB9AMMP13MAOB
SCHEMBL19413155 0.94 MAPT (0.73) MAPTHPGDRAB9AMMP13MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374237-A1 METHOD FOR IMPREGNATING REINFORCING FIBRES WITH POLYARYLETHERKETONES AND SEMI-PRODUCTS OBTAINED THEREFROM ARKEMA FRANCE (FR) 2023-11-23 US disclosed
US-11781017-B2 Blends of polyaryletherketones having improved impact-resistance, elongation at break and flexibility ARKEMA FRANCE (FR) 2023-10-10 US disclosed
US-11746188-B2 Poly(aryl-ether-ketone) (PAEK) powder suitable for multiple use in sintering methods ARKEMA FRANCE (FR) 2023-09-05 US disclosed
US-20230272190-A1 THERMOPLASTIC COMPOSITIONS OF POLYETHERETHERKETONES HAVING IMPROVED TRIBOLOGICAL MATERIAL PROPERTIES AND USE THEREOF EVONIK OPERATIONS GMBH (DE) 2023-08-31 US disclosed
US-20230245796-A1 Insulated conductor for use in a winding, winding derived therefrom and corresponding manufacturing methods ARKEMA FRANCE (FR) 2023-08-03 US disclosed
US-11697718-B2 Method for impregnating reinforcing fibres with polyaryletherketones and semi-products obtained therefrom ARKEMA FRANCE (FR) 2023-07-11 US disclosed
WO-2022117727-A1 PULVERULENT COMPOSITION BASED ON PAEK(S), SINTERING CONSTRUCTION PROCESS AND OBJECT DERIVED THEREFROM ARKEMA FRANCE (FR) 2022-06-09 WO disclosed
EP-3825345-A1 IMPROVED POWDER FOR ADDITIVE MANUFACTURING ARKEMA FRANCE (FR) 2021-05-26 EP disclosed
EP-3237493-B1 PAEK/PPSU/PES COMPOSITIONS SOLVAY SPECIALTY POLYMERS USA (US) 2020-04-29 EP disclosed
EP-2290001-B1 Use of engineering polymer compositions for the manufacture of high performance films SOLVAY SPECIALTY POLYMERS USA (US) 2017-10-11 EP disclosed
US-20070197739-A1 POLY ARYL ETHER KETONE POLYMER BLENDS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-08-23 US disclosed
US-20070149629-A1 Expanded and expandable high glass transition temperature polymers CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-28 US disclosed
US-20070142569-A1 Food service articles of manufacture comprising high temperature polymers CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-21 US disclosed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-20070066765-A1 Polyarlyl ether ketone polymer blends GENERAL ELECTRIC COMPANY (US) 2007-03-22 US disclosed
US-20070066739-A1 Coated articles of manufacture made of high Tg polymer blends GENERAL ELECTRIC COMPANY 2007-03-22 US disclosed
US-20070066741-A1 High glass transition temperature thermoplastic articles CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-7189782-B2 Thermoplastic film, thermoplastic resin composition, and phyllosilicate TEIJIN LIMITED (JP) 2007-03-13 US disclosed
US-7189782-B2 Thermoplastic film, thermoplastic resin composition, and phyllosilicate TEIJIN LIMITED (JP) 2007-03-13 US disclosed