AASDHPPT

L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase · Q9NRN7 · AASDHPPT on Sugi Atlas →

0 patent compounds predicted against AASDHPPT, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AASDHPPT by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Apomorphine Pump in Early Stage of Parkinson's Disease (EARLY-PUMP) PHASE3COMPLETED
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
A Study to Evaluate Efficacy and Safety of Distal Jejunal-release Dextrose Beads Formulation in Subjects With a Pathological Oral Glucose Tolerance Test PHASE2COMPLETED
Serine Supplementation for Obese Subjects With Fatty Liver Disease PHASE1/PHASE2COMPLETED
Aminopterin Pharmacokinetic Study In Moderate to Severe Psoriasis PHASE1COMPLETED
Alanosine in Treating Patients With Progressive or Recurrent Malignant Gliomas PHASE1COMPLETED
The Effect of Acute Lysine Administration on α-aminoadipic Acid (Sub-study) PHASE1COMPLETED
Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria PHASE1COMPLETED
Vitamin D Levels in the Skin of Healthy Subjects After Oral Supplementation PHASE1COMPLETED
An Individual Patient, Open Label Study to Use ACER-001 to Treat Combined D,L-2 Hydroxyglutaric Aciduria (C-2HGA) PHASE1ENROLLING_BY_INVITATION
Lysine Oxidation in Response to Arginine Supplementation nanCOMPLETED
Newborn Screening for Aromatic L-amino Acid Decarboxylase Deficiency nanCOMPLETED
Metabolic Remodeling in Pulmonary Arterial Hypertension (PAH) nanCOMPLETED
Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA) nanRECRUITING
Biomarker for Hypophosphatasia Disease (BioHypophos) nanWITHDRAWN
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD nanUNKNOWN
Observational Study of Acute Intermittent Porphyria Patients nanCOMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
Identification of Acute Intermittent Porphyria Modifying Genes nanRECRUITING
Nutritional Impacts of Palynziq on Patients With Phenylketonuria (PKU) nanRECRUITING
Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies nanRECRUITING
A Prospective Study of the Disease Characteristics of Adult Patients With Long Chain Fatty Acid Oxidation Disorders nanCOMPLETED
Prevalence of High Plasmatic 3OMethyldopa Level in a Specific Population of Patients With a Symptomatology Compatible With AADC Deficiency nanUNKNOWN
Targeting zDHHC Enzymes to Counteract Alzheimer's Disease nanNOT_YET_RECRUITING
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia nanUNKNOWN
Plasma Molecular Profiling in ALK Inhibitor Resistant NSCLC nanCOMPLETED
Unraveling Genetics of HypoPhosPhatasia (HPP Genetics) nanCOMPLETED
Study of Protein Translocation in Patients With Beta-Oxidation Disorders nanCOMPLETED
Tolerability and Efficacy of L-Serine in Patients With GRIN-related Encephalopathy nanUNKNOWN
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a AASDHPPT binder may also engage these)

ProteinNameSimilarity
Q5NVE1 1.000 Q5NVE1 →
B2RYJ4 0.998 B2RYJ4 →
Q9CQF6 0.997 Q9CQF6 →
Q6GQ33 0.964 Q6GQ33 →
Q6NYU2 0.961 Q6NYU2 →
PARN Poly(A)-specific ribonuclease PARN 0.961 landscape →
B4G0F3 0.960 B4G0F3 →
GLS2 Glutaminase liver isoform, mitochondrial 0.960 landscape →
Q5R962 0.959 Q5R962 →
Q8VDG3 0.959 Q8VDG3 →
E9Q4Z2 0.959 E9Q4Z2 →
Q5RC51 0.958 Q5RC51 →
Q5BJZ6 0.958 Q5BJZ6 →
Q5IH13 0.958 Q5IH13 →
P69341 0.958 P69341 →
Q5ZKY2 0.958 Q5ZKY2 →
Q05B63 0.957 Q05B63 →
Q5F480 0.957 Q5F480 →
B0K012 0.957 B0K012 →
Q9CWH5 0.957 Q9CWH5 →
A6H7H7 0.957 A6H7H7 →
Q6GR37 0.957 Q6GR37 →
A0FKG7 0.957 A0FKG7 →
Q80YV4 0.957 Q80YV4 →
F1N9S8 0.957 F1N9S8 →
Q9UK99 0.956 Q9UK99 →
C6JS30 0.955 C6JS30 →
Q80UY1 0.955 Q80UY1 →
P82922 0.955 P82922 →
Q94E75 0.955 Q94E75 →