ADAR

Double-stranded RNA-specific adenosine deaminase · P55265 · ADAR on Sugi Atlas →

0 patent compounds predicted against ADAR, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ADAR by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Acelarin First Line Randomised Pancreatic Study PHASE2/PHASE3SUSPENDED
UNITY 3: A Japanese Phase 3 Study of a Daclatasvir/Asunaprevir/BMS-791325 in Subjects With Genotype 1 Chronic Hepatitis C PHASE3COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Antifolate Effectiveness in Arthritis PHASE2COMPLETED
Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patients PHASE1/PHASE2COMPLETED
Alanosine in Treating Patients With Cancer PHASE2COMPLETED
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
University of California, San Diego (UCSD) Suramin Autism Treatment-1 (SAT1) Trial PHASE1/PHASE2COMPLETED
Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema PHASE2COMPLETED
5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors PHASE1RECRUITING
Treatment of SCID Due to ADA Deficiency With Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells After Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector PHASE1COMPLETED
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors PHASE1COMPLETED
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors PHASE1COMPLETED
Evaluation of the Safety, Tolerability, and Efficacy of LE051 in Patients With Duchenne Muscular Dystrophy EARLY_PHASE1RECRUITING
A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients EARLY_PHASE1RECRUITING
Observational Study Evaluating the Prevalence of Enzyme Deficiency in Pulmonology Clinics (ADA) nanUNKNOWN
Prevalence of Adenosine Deaminase (ADA) Enzyme Deficiency Disease in Adult Patients With Pulmonary Alveolar Proteinosis nanUNKNOWN
Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E nanUNKNOWN
ADAR1 Expression Level in Rectal Cancer nanRECRUITING
Investigation of ADA Enzyme Deficiency nanUNKNOWN
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Effect of Polymorphisms in the Adenosine a2a Receptor Gene and AMPD2 Gene on Adenosine-Induced Vasodilation and Reactive Hyperemia nanCOMPLETED
Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart nanUNKNOWN
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
Determination of the Effectiveness of Oral Chlorine Dioxide in the Treatment of COVID 19 nanUNKNOWN
Role of ADA SNPs in Subjects With Relapsing Multiple Sclerosis (RMS) nanUNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Impact Of Choline in Patients With NAFLD nanUNKNOWN
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a ADAR binder may also engage these)

ProteinNameSimilarity
P55266 1.000 P55266 →
Q99MU3 0.997 Q99MU3 →
Q9H694 0.987 Q9H694 →
Q80TJ7 0.987 Q80TJ7 →
Q8TEW8 0.986 Q8TEW8 →
Q8K4S7 0.986 Q8K4S7 →
Q9EQM6 0.986 Q9EQM6 →
ERCC5 DNA excision repair protein ERCC-5 0.985 landscape →
Q5F3F2 0.985 Q5F3F2 →
Q8WY91 0.985 Q8WY91 →
Q5QJC2 0.984 Q5QJC2 →
Q5R6Z9 0.984 Q5R6Z9 →
Q6GQL0 0.984 Q6GQL0 →
Q9BY84 0.984 Q9BY84 →
Q62925 0.984 Q62925 →
Q69Z66 0.984 Q69Z66 →
Q501R9 0.984 Q501R9 →
Q6AYH3 0.984 Q6AYH3 →
O88974 0.984 O88974 →
Q9R207 0.983 Q9R207 →
Q8BJ34 0.983 Q8BJ34 →
Q8NE18 0.983 Q8NE18 →
Q9NP66 0.983 Q9NP66 →
F6RIX4 0.983 F6RIX4 →
Q7TPQ3 0.983 Q7TPQ3 →
Q5NVC7 0.983 Q5NVC7 →
P79457 0.982 P79457 →
Q5R6F3 0.982 Q5R6F3 →
Q6A0A9 0.982 Q6A0A9 →
Q76CY8 0.982 Q76CY8 →