ALDH18A1

Delta-1-pyrroline-5-carboxylate synthase · P54886 · ALDH18A1 on Sugi Atlas →

0 patent compounds predicted against ALDH18A1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ALDH18A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Identification of Polymorphisms Involved in the Metabolism of Propofol PHASE4COMPLETED
ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) PHASE4UNKNOWN
Folate Rechallenge PHASE2COMPLETED
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients nanRECRUITING
Functional Investigation of Endothelial Function and Regenerative Cell Exhaustion nanNOT_YET_RECRUITING
Mutation Analysis of 17α-Hydroxylase nanUNKNOWN
Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population nanUNKNOWN
Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies nanRECRUITING
Pharmacogenetic and Neurofunctional Brain Areas Study in Obese Patients With Binge Eating Disorder nanUNKNOWN
ALDH2 Genetic Testing in East Asian Community nanNOT_YET_RECRUITING
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Pharmacogenetic Determinants Of Treatment Response In Children nanRECRUITING
Polycystic Ovary Syndrome in Type 1 Diabetes nanNOT_YET_RECRUITING
Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China nanCOMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
Pharmacogenomics of Antidepressant Response in Children and Adolescents nanCOMPLETED
The Enzymatic Activity of Lymphocyte Dihydropyrimidine Dehydrogenase DPD in the Blood as a Predictive and Prognostic Factor in Patients With Digestive Cancer in the First or Second Metastatic Line nanUNKNOWN
Albumin, Total and Free Fraction of Mycophenolic Acid, and Measurement of IMPDH Activity in Liver Transplants. nanCOMPLETED
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients. nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3 nanCOMPLETED
Identification of Acute Intermittent Porphyria Modifying Genes nanRECRUITING
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
Tamoxifen Pharmacogenetics in Asian Breast Cancer Women nanUNKNOWN
Genetic and Environmental Risk Factors Related to Esophageal Cancer nanACTIVE_NOT_RECRUITING
Clinical Pharmacogenomics of Antidepressant Response nanCOMPLETED
Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis nanCOMPLETED
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle nanCOMPLETED
Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ALDH18A1 binder may also engage these)

ProteinNameSimilarity
Q5R4M8 1.000 Q5R4M8 →
Q9Z110 1.000 Q9Z110 →
P54889 0.997 P54889 →
P00927 0.990 P00927 →
Q42777 0.990 Q42777 →
Q2QMG2 0.989 Q2QMG2 →
Q9ZUG4 0.988 Q9ZUG4 →
B8M7D2 0.988 B8M7D2 →
Q5R5P3 0.987 Q5R5P3 →
Q5B590 0.987 Q5B590 →
B2VZQ8 0.987 B2VZQ8 →
A1CY38 0.987 A1CY38 →
A6ZQ59 0.987 A6ZQ59 →
A0A7J6G7L9 0.987 A0A7J6G7L9 →
Q9T079 0.987 Q9T079 →
Q7ZXP9 0.987 Q7ZXP9 →
Q09509 0.986 Q09509 →
B0Y5C3 0.986 B0Y5C3 →
P38627 0.986 P38627 →
Q4WNI1 0.986 Q4WNI1 →
Q5XHA8 0.986 Q5XHA8 →
B9KHF1 0.986 B9KHF1 →
A2ZCP0 0.986 A2ZCP0 →
C4JWQ7 0.986 C4JWQ7 →
Q5PBX6 0.986 Q5PBX6 →
Q1RMS2 0.986 Q1RMS2 →
Q6FUD0 0.986 Q6FUD0 →
P14882 0.986 P14882 →
P0DTA4 0.985 P0DTA4 →
Q9VUL1 0.985 Q9VUL1 →