AMD1

S-adenosylmethionine decarboxylase proenzyme · P17707 · AMD1 on Sugi Atlas →

4,494 patent compounds predicted against AMD1, 3,528 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Sulfuric Acid (SCHEMBL955085)	1.00	16/20
Sulfuric Acid (SCHEMBL955088)	1.00	16/20
Sulfuric Acid (SCHEMBL955588)	1.00	16/20
Sulfuric Acid (SCHEMBL955592)	1.00	16/20
Sulfuric Acid (SCHEMBL956813)	1.00	16/20
Sulfuric Acid (SCHEMBL956821)	1.00	16/20
Sulfuric Acid (SCHEMBL955667)	0.93	16/20
Sulfuric Acid (SCHEMBL955671)	0.93	16/20
SCHEMBL953607	0.91	16/20
SCHEMBL955087	0.82	16/20
SCHEMBL955590	0.81	16/20
SCHEMBL956819	0.80	16/20
Sulfuric Acid (SCHEMBL954339)	0.80	16/20
SCHEMBL955669	0.78	16/20
SCHEMBL3119207	0.69	16/20
SCHEMBL3119222	0.69	16/20
SCHEMBL3265005	0.68	16/20
SCHEMBL954338	0.64	16/20
SCHEMBL953273	0.64	16/20
SCHEMBL953274	0.64	16/20

Clinical trials — most relevant to AMD1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Trial of CM-AT in Children With Autism With All Levels of FCT (The Blum Study)	PHASE3	COMPLETED
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor	PHASE1/PHASE2	NOT_YET_RECRUITING
Study of SGN1 in Patients With Advanced Solid Tumor	PHASE1/PHASE2	RECRUITING
Study of SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumor	PHASE1/PHASE2	RECRUITING
Folate Rechallenge	PHASE2	COMPLETED
Treatment With Azacitidine of Recurrent Gliomas With IDH1/2 Mutation	PHASE2	UNKNOWN
Effects of Vitamin B3 in Patients With Ataxia Telangiectasia	PHASE2	COMPLETED
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors	PHASE1	COMPLETED
Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels	nan	COMPLETED
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer	nan	UNKNOWN
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients.	nan	COMPLETED
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients	nan	COMPLETED
Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart	nan	UNKNOWN
Clinical and Laboratory Study of Methylmalonic Acidemia	nan	RECRUITING
Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD	nan	NOT_YET_RECRUITING
Harmonized Micronutrient Project	nan	COMPLETED
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD	nan	UNKNOWN
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside	nan	UNKNOWN
The Role of Transthoracic Echocardiography in Diagnosis of Pulmonary Hypertension of Infants With Bronchopulmonary Dysplasia	nan	COMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia	nan	RECRUITING
DNA Methylation and Autoimmune Thyroid Diseases	nan	COMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
Treating Oxidative Stress and the Metabolic Pathology of Autism	nan	COMPLETED
Dietary Effects of Sulfur Amino Acids	nan	COMPLETED
Impact Of Choline in Patients With NAFLD	nan	UNKNOWN
Presence of Cyclopropane Fatty Acids (CPFA) in Human Plasma	nan	COMPLETED
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation	nan	COMPLETED
Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)	nan	RECRUITING
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD	nan	COMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a AMD1 binder may also engage these)

Protein	Name	Similarity
P82185	—	1.000	P82185 →
P17708	—	1.000	P17708 →
P0DMN7	—	1.000	P0DMN7 →
P50243	—	1.000	P50243 →
P28918	—	1.000	P28918 →
P79888	—	1.000	P79888 →
D3Z6H8	—	1.000	D3Z6H8 →
Q641Y5	—	0.970	Q641Y5 →
E9Q4Z2	—	0.969	E9Q4Z2 →
Q6YXZ7	—	0.968	Q6YXZ7 →
Q6ESI7	—	0.967	Q6ESI7 →
Q04499	—	0.967	Q04499 →
A8KB34	—	0.967	A8KB34 →
F4JVN6	—	0.967	F4JVN6 →
AGL	Glycogen debranching enzyme	0.967	landscape →
Q94A08	—	0.966	Q94A08 →
Q9LXT9	—	0.966	Q9LXT9 →
Q9SE94	—	0.966	Q9SE94 →
Q9D906	—	0.966	Q9D906 →
A2X0Q3	—	0.966	A2X0Q3 →
PRMT5	Protein arginine N-methyltransferase 5	0.966	landscape →
Q9FGS4	—	0.966	Q9FGS4 →
NAT10	RNA cytidine acetyltransferase	0.966	landscape →
Q5R981	—	0.966	Q5R981 →
Q9FQ11	—	0.965	Q9FQ11 →
Q5ZKY2	—	0.965	Q5ZKY2 →
Q75HE6	—	0.965	Q75HE6 →
P35574	—	0.965	P35574 →
Q8N1G2	—	0.965	Q8N1G2 →
F4JP46	—	0.965	F4JP46 →