AP3S1

AP-3 complex subunit sigma-1 · Q92572 · AP3S1 on Sugi Atlas →

0 patent compounds predicted against AP3S1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AP3S1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients PHASE3ACTIVE_NOT_RECRUITING
Evaluate Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients PHASE3COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
A Study of APX3330 in Patients With Advanced Solid Tumors PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Weight Variation on Cop nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome nanRECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Susceptibility Genes in Autism Spectrum Disorders nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial nanCOMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Exploring the Genetics of Neuropathic Pain nanRECRUITING
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Quantification of GADD34 Expression in RA nanCOMPLETED
AutoInflammatory Disease Alliance Registry (AIDA) nanRECRUITING
Analysis of Post-Translational Modifications of a Critical Protein Implicated in Amyotrophic Lateral Sclerosis nanCOMPLETED
Exploring the Role of Neuroactive Steroids in Tourette Syndrome nanUNKNOWN
Immune Cell Response to Stimuli nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a AP3S1 binder may also engage these)

ProteinNameSimilarity
Q2YDH6 1.000 Q2YDH6 →
Q9DCR2 1.000 Q9DCR2 →
Q8BSZ2 0.937 Q8BSZ2 →
Q1JQA3 0.936 Q1JQA3 →
Q6DEG4 0.936 Q6DEG4 →
P59780 0.935 P59780 →
Q5RDP9 0.935 Q5RDP9 →
O54984 0.933 O54984 →
G3V9T7 0.933 G3V9T7 →
A5PJI5 0.933 A5PJI5 →
Q13888 0.932 Q13888 →
GET3 ATPase GET3 0.932 landscape →
P35585 0.932 P35585 →
Q2KJ81 0.931 Q2KJ81 →
Q2KHU8 0.930 Q2KHU8 →
Q32Q06 0.930 Q32Q06 →
B2RYU6 0.930 B2RYU6 →
Q2TBV5 0.930 Q2TBV5 →
Q6P1K8 0.930 Q6P1K8 →
AP1M1 AP-1 complex subunit mu-1 0.930 landscape →
Q2VIR3 0.929 Q2VIR3 →
C9WPN6 0.929 C9WPN6 →
Q7ZXB7 0.929 Q7ZXB7 →
Q9JIB4 0.929 Q9JIB4 →
B5FXJ6 0.928 B5FXJ6 →
Q9Z0N2 0.928 Q9Z0N2 →
F1QGW6 0.928 F1QGW6 →
Q5R797 0.927 Q5R797 →
Q95140 0.927 Q95140 →
Q5ZMS3 0.927 Q5ZMS3 →