ATP6V1E1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to ATP6V1E1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Possible Efficacy and Safety of Lansoprazole Co-administration With Neoadjuvant Chemotherapy in Women With Breast Cancer	PHASE3	COMPLETED
BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases	PHASE2/PHASE3	WITHDRAWN
Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation	PHASE2/PHASE3	UNKNOWN
Copper Histidine Therapy for Menkes Diseases	PHASE1/PHASE2	COMPLETED
Natural History Study of ATP1A3-related Disease	nan	UNKNOWN
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts	nan	COMPLETED
Prescreening Study to Identify Potential Wilson Disease Participants for Gene-Editing Clinical Trial	nan	ACTIVE_NOT_RECRUITING
Genetic Analysis of Patients With Pseudoxanthoma Elasticum	nan	COMPLETED
Role for Biochemical Assays and Kayser-Fleischer Rings in Diagnosis of Wilson Disease	nan	RECRUITING
Establishment of Human Cellular Disease Models for Wilson Disease	nan	COMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Pediatric Cardiomyopathy Mutation Analysis	nan	RECRUITING
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Exome Analysis in Hearing Impaired Patients	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Correlation Between Peri-implantitis and Assumptions of Medications	nan	COMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance	nan	COMPLETED
Genetic Testing in Detection of Late-Onset Hearing Loss	nan	COMPLETED
Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias	nan	COMPLETED
DEFINING THE GENETIC DRIVERS OF ADULT-ONSET CHOLESTATIC LIVER DISEASE	nan	RECRUITING
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients	nan	ACTIVE_NOT_RECRUITING
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease	nan	COMPLETED
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae	nan	ACTIVE_NOT_RECRUITING
Haptoglobin Phenotype, Vitamin E and High-density Lipoprotein (HDL) Function in Type 1 Diabetes	nan	COMPLETED
the Effect of ABCC2 Genetic Polymorphism on Neurotoxicity in Gastrointestinal Cancer Patients Receiving Oxaliplatin	nan	UNKNOWN
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a ATP6V1E1 binder may also engage these)

Protein	Name	Similarity
P50518	—	1.000	P50518 →
Q6PCU2	—	1.000	Q6PCU2 →
Q4R761	—	1.000	Q4R761 →
P11019	—	1.000	P11019 →
P31402	—	0.996	P31402 →
P54611	—	0.994	P54611 →
Q32LB7	—	0.984	Q32LB7 →
Q96A05	—	0.982	Q96A05 →
Q9C9Z8	—	0.981	Q9C9Z8 →
Q01278	—	0.980	Q01278 →
Q9D593	—	0.979	Q9D593 →
Q95X44	—	0.978	Q95X44 →
Q9U1G5	—	0.978	Q9U1G5 →
O94072	—	0.971	O94072 →
O23948	—	0.961	O23948 →
Q29G21	—	0.955	Q29G21 →
P22203	—	0.954	P22203 →
F4HQD4	—	0.954	F4HQD4 →
Q5M7J9	—	0.954	Q5M7J9 →
Q5ZLX2	—	0.954	Q5ZLX2 →
Q4X0I8	—	0.954	Q4X0I8 →
Q5AZQ5	—	0.953	Q5AZQ5 →
P56286	—	0.953	P56286 →
Q2UF96	—	0.953	Q2UF96 →
Q8W207	—	0.953	Q8W207 →
O13687	—	0.953	O13687 →
P0CAN7	—	0.952	P0CAN7 →
P45437	—	0.952	P45437 →
P68102	—	0.952	P68102 →
Q6ZWX6	—	0.952	Q6ZWX6 →