Sugi Predict

Sugi Predict / Targets / AUP1

AUP1

Lipid droplet-regulating VLDL assembly factor AUP1 · Q9Y679 · AUP1 on Sugi Atlas →

0 patent compounds predicted against AUP1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AUP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Acute Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon PHASE4COMPLETED
Pilot HCV Direct Acting Antiviral Therapy and Metabolism PHASE4COMPLETED
Mechanisms of Lipodystrophy in HIV-Infected Pateints PHASE4COMPLETED
Comparative Study Between Obeticholic Acid Versus Vitamin E in Patients with Non-alcoholic Steatohepatitis PHASE2ACTIVE_NOT_RECRUITING
Cholic Acid for Hepatic Steatosis in Lipodystrophy PHASE2COMPLETED
Choline Effects - Pre-symptomatic AD PHASE1COMPLETED
Insulin Regulation of Lipolysis and Lipolysis Proteins EARLY_PHASE1RECRUITING
Apolipoprotein CIII Reduction Via Colchicine EARLY_PHASE1COMPLETED
The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients nanUNKNOWN
Association of SGLT2 Inhibitors Therapy With Elastographic and Molecular Markers of Liver Injury in Type 2 Diabetes nanCOMPLETED
Role of Dairy Products in Weight Maintenance nanCOMPLETED
In Vivo Metabolism of apoB-containing Lipoproteins in ANGPTL3 Deficient Subjects nanUNKNOWN
A Study to Assess Variation in Potential Biomarkers in Friedreich Ataxia nanCOMPLETED
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Triglyceride-rich LIPoproteins and INflammatory Cytokines After Oral FAT Loading as Potential Early Biomarkers of the Risk of Progression Towards DIABETES and Development of Complications. LIPINFAT Diabetes Study. nanRECRUITING
Epidemiology of Atherosclerosis nanCOMPLETED
Genetic and Environmental Determinants of Triglycerides (GOLDN) nanCOMPLETED
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract nanUNKNOWN
Effect of Laparoscopic Splenectomy on Lipid Profiles in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up) nanNOT_YET_RECRUITING
Genetics of Low Density Lipoprotein Subclasses in Hypercholesterolemia nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry Bad Cholesterol in the Blood nanCOMPLETED
Advanced Lipoproptein Profiling and Cardiovascular Risk Stratification in Familial Hypercholesterolemia nanUNKNOWN
Pharmacogenetics of Hypertriglyceridemia in Hispanics nanCOMPLETED
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk nanCOMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
Gene Expression in Obesity and Insulin Resistance nanCOMPLETED
Impact Of Choline in Patients With NAFLD nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a AUP1 binder may also engage these)

ProteinNameSimilarity
A1L134 — 1.000 A1L134 →
P70295 — 1.000 P70295 →
A9ULG4 — 0.989 A9ULG4 →
Q643R3 — 0.979 Q643R3 →
Q6PBN5 — 0.979 Q6PBN5 →
ABHD16A Phosphatidylserine lipase ABHD16A 0.976 landscape →
LPCAT1 Lysophosphatidylcholine acyltransferase 1 0.975 landscape →
Q5NVK5 — 0.974 Q5NVK5 →
Q6NUI2 — 0.974 Q6NUI2 →
B2RUP2 — 0.974 B2RUP2 →
Q8C0R7 — 0.973 Q8C0R7 →
Q1JPD2 — 0.972 Q1JPD2 →
Q14DK4 — 0.972 Q14DK4 →
TEX264 Testis-expressed protein 264 0.971 landscape →
Q6PDS3 — 0.971 Q6PDS3 →
Q9D2Q2 — 0.971 Q9D2Q2 →
MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 0.971 landscape →
Q8N0W3 — 0.971 Q8N0W3 →
B1H1N7 — 0.971 B1H1N7 →
Q8BYR1 — 0.971 Q8BYR1 →
Q9HBU9 — 0.970 Q9HBU9 →
Q4R8P0 — 0.970 Q4R8P0 →
Q9UNS1 — 0.970 Q9UNS1 →
O89109 — 0.970 O89109 →
Q5TM59 — 0.970 Q5TM59 →
Q1HAQ0 — 0.969 Q1HAQ0 →
TRPM4 Transient receptor potential cation channel subfamily M member 4 0.969 landscape →
Q61161 — 0.969 Q61161 →
TELO2 Telomere length regulation protein TEL2 homolog 0.968 landscape →
Q6NVG1 — 0.968 Q6NVG1 →