C1QBP

Complement component 1 Q subcomponent-binding protein, mitochondrial · Q07021 · C1QBP on Sugi Atlas →

0 patent compounds predicted against C1QBP, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to C1QBP by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS PHASE4COMPLETED
Safety and Effectiveness of h5G1.1-mAb for Dermatomyositis PHASE2COMPLETED
A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas PHASE2COMPLETED
Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH) PHASE2COMPLETED
Eculizumab Therapy for Dense Deposit Disease and C3 Nephropathy PHASE1COMPLETED
Phase 1 Study of HS-20152 in Healthy Participants PHASE1NOT_YET_RECRUITING
C1-esterase Inhibitor (Cinryze) for Acute Treatment of Neuromyelitis Optica Exacerbation PHASE1COMPLETED
First-in-Human (FIH) Clinical Study of NM8074 in Healthy Adult Volunteers PHASE1COMPLETED
Recombinant Human Mannose-Binding Lectin (MBL) in Treating Young Patients With MBL Deficiency and Fever and Neutropenia PHASE1WITHDRAWN
The Use of Eculizumab in HELLP Syndrome PHASE1COMPLETED
TP10 Use in Patients With C3 Glomerulopathy (C3G) PHASE1WITHDRAWN
First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers PHASE1COMPLETED
Anti-C1s, Anti-HMGB1 and Anti-C1q Autoantibodies in Systemic Lupus Erythematosus (DYSALARM-322) nanRECRUITING
Evaluation of Interleukine 6 (and Other Cytokines and Inflammatory Markers) in COVID-19 Patients With a Systemic Inflammatory Response Syndrome nanCOMPLETED
Complement C5a Receptors in Hidradenitis Suppurativa nanCOMPLETED
Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease nanCOMPLETED
Study of Genetic Anomalies of Complement Related Proteins in Patients With IgA Glomerulonephritis nanCOMPLETED
Complement Activation in the Lysosomal Storage Disorders nanWITHDRAWN
DKK-3 rs11544814 and CFH rs10737680 Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CAD nanUNKNOWN
Role of Renal Artery Doppler in Critically Ill Children With Acute Kidney Injury nanUNKNOWN
Effect of Platelet Storage on Complement Activation nanUNKNOWN
Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Precision Medicine Phase 2 Option 1 nanACTIVE_NOT_RECRUITING
Neuro-Inflammation in Extremity Trauma: Risk Verification in Elbow Trauma: The NERVE Study nanNOT_YET_RECRUITING
New Analytic Tools for aHUS and C3G Diagnosis nanACTIVE_NOT_RECRUITING
Immune System in Diabetic Kidney Disease nanENROLLING_BY_INVITATION
A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis nanCOMPLETED
Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests nanUNKNOWN
Sources of COmplement in Meningococcal and Pertussis Serum Bactericidal Antibody Assays nanUNKNOWN
Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department nanCOMPLETED
Proadrenomedullin for Early Risk Assessment in the Emergency Department nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a C1QBP binder may also engage these)

ProteinNameSimilarity
Q9MZE0 1.000 Q9MZE0 →
O35796 1.000 O35796 →
Q3T0B6 1.000 Q3T0B6 →
O35658 1.000 O35658 →
O94675 0.988 O94675 →
A1L1P7 0.987 A1L1P7 →
Q68FS3 0.986 Q68FS3 →
Q8N668 0.985 Q8N668 →
Q8VDT9 0.985 Q8VDT9 →
Q61733 0.985 Q61733 →
A8IYS6 0.985 A8IYS6 →
B5E0H4 0.984 B5E0H4 →
Q863Z0 0.984 Q863Z0 →
Q8N5N7 0.984 Q8N5N7 →
PSME2 Proteasome activator complex subunit 2 0.984 landscape →
Q5ZLC1 0.984 Q5ZLC1 →
P97372 0.983 P97372 →
A6ZND9 0.983 A6ZND9 →
P82925 0.983 P82925 →
B3LIY9 0.983 B3LIY9 →
Q8WTJ4 0.983 Q8WTJ4 →
Q6PD74 0.983 Q6PD74 →
Q5E9G3 0.983 Q5E9G3 →
O59797 0.983 O59797 →
Q54JD2 0.983 Q54JD2 →
Q3U1N2 0.983 Q3U1N2 →
Q9W549 0.983 Q9W549 →
B3LSV9 0.983 B3LSV9 →
A6ZTA5 0.983 A6ZTA5 →
A7MBC2 0.983 A7MBC2 →