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Sugi Predict / Targets / CCDC6

CCDC6

Coiled-coil domain-containing protein 6 (Papi · Q16204 · CCDC6 on Sugi Atlas →

9,905 patent compounds predicted against CCDC6, 7,795 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL584891 SCHEMBL584891 0.58 2/20
SCHEMBL1893324 SCHEMBL1893324 0.47 2/20
Cabozantinib Cabozantinib (SCHEMBL360795) 1.00 1/20
Lenvatinib Lenvatinib (SCHEMBL864638) 1.00 1/20
Cep-32496 Cep-32496 (SCHEMBL1015932) 1.00 1/20
Lenvatinib Lenvatinib (SCHEMBL1389214) 0.98 1/20
Lenvatinib Lenvatinib (SCHEMBL865174) 0.94 1/20
SCHEMBL1011649 SCHEMBL1011649 0.91 1/20
SCHEMBL1011900 SCHEMBL1011900 0.90 1/20
SCHEMBL1013252 SCHEMBL1013252 0.90 1/20
SCHEMBL1012434 SCHEMBL1012434 0.88 1/20
SCHEMBL903105 SCHEMBL903105 0.88 1/20
SCHEMBL1248140 SCHEMBL1248140 0.87 1/20
SCHEMBL371833 SCHEMBL371833 0.86 1/20
SCHEMBL1894427 SCHEMBL1894427 0.86 1/20
SCHEMBL1894913 SCHEMBL1894913 0.86 1/20
SCHEMBL864156 SCHEMBL864156 0.85 1/20
SCHEMBL863487 SCHEMBL863487 0.85 1/20
SCHEMBL1012302 SCHEMBL1012302 0.85 1/20
SCHEMBL371922 SCHEMBL371922 0.84 1/20

Clinical trials — most relevant to CCDC6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype EARLY_PHASE1COMPLETED
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies nanRECRUITING
PCD New Gene Discovery nanCOMPLETED
Identification of Genetic Basis of Atrioventricular Conduction Defects: From Congenital Forms to Degenerative Forms nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Genomic Study of Congenital Malformation nanUNKNOWN
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
Genotype/Phenotype Correlation With Focus on Lung Function in Primary Ciliary Dyskinesia (PCD) nanUNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) nanCOMPLETED
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
CABP2 Patient Registry and Natural History Study nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Genetic Epidemiology of Asthma in Costa Rica nanCOMPLETED
Shanghai High Myopia Study nanRECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Genetic Diagnosis in Congenital Cataracts nanCOMPLETED
Corpus Callosum Agenesis and Intellectual Disability nanCOMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia nanCOMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders nanRECRUITING
Study of Skeletal Disorders and Short Stature nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CCDC6 binder may also engage these)

ProteinNameSimilarity
D3YZP9 — 0.998 D3YZP9 →
Q6DHL7 — 0.987 Q6DHL7 →
Q0V989 — 0.987 Q0V989 →
Q4V872 — 0.985 Q4V872 →
Q69ZZ6 — 0.984 Q69ZZ6 →
O43439 — 0.984 O43439 →
Q80W04 — 0.984 Q80W04 →
Q9HAU0 — 0.983 Q9HAU0 →
Q7PQ25 — 0.983 Q7PQ25 →
Q8R310 — 0.983 Q8R310 →
Q62415 — 0.982 Q62415 →
Q02225 — 0.982 Q02225 →
U3JAG9 — 0.982 U3JAG9 →
Q8VHG2 — 0.982 Q8VHG2 →
P49140 — 0.982 P49140 →
Q3LGD4 — 0.981 Q3LGD4 →
Q7KW14 — 0.981 Q7KW14 →
Q96KQ4 — 0.981 Q96KQ4 →
Q99LJ0 — 0.981 Q99LJ0 →
Q9ULS5 — 0.981 Q9ULS5 →
A4IIE8 — 0.981 A4IIE8 →
Q13136 — 0.981 Q13136 →
Q96G01 — 0.981 Q96G01 →
O94876 — 0.980 O94876 →
Q5R8Q4 — 0.980 Q5R8Q4 →
Q0P485 — 0.980 Q0P485 →
Q91Z80 — 0.980 Q91Z80 →
Q4VCS5 — 0.980 Q4VCS5 →
Q09YG9 — 0.980 Q09YG9 →
Q9Z136 — 0.980 Q9Z136 →