CCR2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL88313	0.81	20/20
SCHEMBL88314	0.81	20/20
SCHEMBL128653	0.63	20/20
SCHEMBL306044	0.64	18/20
SCHEMBL306286	0.60	18/20
SCHEMBL306214	0.60	18/20
SCHEMBL306504	0.60	18/20
SCHEMBL304956	0.57	18/20
SCHEMBL306049	0.50	18/20
SCHEMBL242474	1.00	17/20
SCHEMBL304919	0.62	17/20
SCHEMBL306522	0.56	17/20
SCHEMBL306037	0.54	17/20
SCHEMBL305758	0.54	17/20
SCHEMBL305649	0.53	17/20
SCHEMBL305709	0.52	17/20
SCHEMBL306097	0.52	17/20
SCHEMBL306107	0.52	17/20
SCHEMBL305386	0.51	17/20
SCHEMBL305648	0.51	17/20

Clinical trials — most relevant to CCR2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Rapid Effects Linagliptin on Monocyte Polarization and Endothelial Progenitor Cells in Type 2 Diabetes	PHASE4	COMPLETED
Leronlimab in Moderately Ill Patients With COVID-19 Pneumonia	PHASE3	SUSPENDED
Leronlimab in Patients With Coronavirus Disease 2019 (COVID-19) With Need for Mechanical Ventilation or Extracorporeal Membrane Oxygenation	PHASE3	SUSPENDED
Effect of Cenicriviroc on HIV Neurocognitive Impairment	PHASE2	COMPLETED
Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients	PHASE1/PHASE2	COMPLETED
Effect of Galantamine on Inflammation and Cognition	PHASE2	COMPLETED
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients	PHASE2	COMPLETED
Pre-operative Stereotactic Body Radiation Therapy for Pancreatic Adenocarcinoma With or Without CCX872-B	PHASE1/PHASE2	WITHDRAWN
A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)	PHASE1	RECRUITING
A Phase I Clinical Trial to Evaluate the Effect of Renal Impairment on Pharmacokinetics of NOX-E36	PHASE1	COMPLETED
NIH CCR2 AAA Study	EARLY_PHASE1	COMPLETED
Genetic Polymorphism Associated With Coronary Heart Disease Susceptibility and Variability of Clopidogrel Response	nan	ACTIVE_NOT_RECRUITING
Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure	nan	UNKNOWN
Inflammatory Biomarkers in Seizure	nan	UNKNOWN
Circular RNA and Chemerin in Breast Cancer Patient	nan	UNKNOWN
Fetal Cell Receptors Repertoire	nan	RECRUITING
Evaluation of CCR6 Gene Expression and Circulating CCL20 Levels as Potential Biomarkers in Rheumatoid Arthritis	nan	NOT_YET_RECRUITING
Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker	nan	COMPLETED
Lung-Resident Memory Th2 Cells in Asthma	nan	ACTIVE_NOT_RECRUITING
The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma	nan	UNKNOWN
IL-11 in the Development of Multiple Sclerosis	nan	UNKNOWN
The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma	nan	UNKNOWN
Monocyte Chemoattractant Protein-1 in Psoriatic Arthritis Patients	nan	UNKNOWN
Subclinical Cytomegalovirus Reactivation in Acute ANCA-associated Vasculitis	nan	ACTIVE_NOT_RECRUITING
LoViReT (Low Viral Reservoir Treated Patients)	nan	COMPLETED
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia	nan	UNKNOWN
Immunology Dysregulation in Lymphadenitis Tuberculosis : An Observational Study Using Patient' Block Paraffins 2019 Until 2021	nan	COMPLETED
Evaluating the Role of Pre-existing Resolvins in the Resolution of ICU Delirium	nan	WITHDRAWN
Preoperative Risk Factors and Perioperative Neurocognitive Disorders	nan	COMPLETED
Involvement of Skeletal Muscle Fibrocytes in sarcOpenia in Patients With Chronic ObstRuctive Pulmonary Disease	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CCR2 binder may also engage these)

Protein	Name	Similarity
P51676	—	0.997	P51676 →
O54814	—	0.997	O54814 →
Q2Y2P0	—	0.996	Q2Y2P0 →
P56482	—	0.995	P56482 →
Q64H34	—	0.995	Q64H34 →
P35411	—	0.994	P35411 →
CCR1	C-C chemokine receptor type 1	0.994	landscape →
Q764M9	—	0.994	Q764M9 →
Q95NC8	—	0.994	Q95NC8 →
Q6WN98	—	0.994	Q6WN98 →
P56493	—	0.994	P56493 →
Q9BDS8	—	0.994	Q9BDS8 →
P51683	—	0.994	P51683 →
Q89609	—	0.994	Q89609 →
Q8HZU0	—	0.993	Q8HZU0 →
Q95NC2	—	0.993	Q95NC2 →
Q95NC6	—	0.993	Q95NC6 →
A6QNL7	—	0.993	A6QNL7 →
P56491	—	0.993	P56491 →
Q9YGC3	—	0.993	Q9YGC3 →
Q95NC0	—	0.993	Q95NC0 →
Q9TV47	—	0.993	Q9TV47 →
Q3LSL6	—	0.992	Q3LSL6 →
Q9BGN6	—	0.992	Q9BGN6 →
Q95NC4	—	0.992	Q95NC4 →
O97878	—	0.992	O97878 →
P68269	—	0.992	P68269 →
O18793	—	0.992	O18793 →
Q1ZY22	—	0.992	Q1ZY22 →
Q07FZ4	—	0.992	Q07FZ4 →