CFAP410 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to CFAP410 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety	PHASE2	COMPLETED
Study of Inhaled RCT1100 in Adults With PCD Caused by Pathogenic Mutations in the DNAI1 Gene to Measure Mucociliary Clearance	PHASE1	COMPLETED
A Study to Assess the Safety, Tolerability, Ciliary Rescue, and Pharmacodynamics of RCT1100 in Adults With PCD	PHASE1	COMPLETED
Study Evaluating the Safety and Tolerability of RCT1100 in Healthy and PCD Subjects	PHASE1	COMPLETED
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype	EARLY_PHASE1	COMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Genotype/Phenotype Correlation With Focus on Lung Function in Primary Ciliary Dyskinesia (PCD)	nan	UNKNOWN
Early Detection and Characterization of Primary Ciliary Dyskinesia	nan	UNKNOWN
Primary Ciliary Dyskinesia in Adult Bronchiectasis	nan	NOT_YET_RECRUITING
Genetic Diagnosis in Congenital Cataracts	nan	COMPLETED
A Study Providing Genetic Testing to Find Those Who May Have Primary Ciliary Dyskinesia for Potential Clinical Trials	nan	ACTIVE_NOT_RECRUITING
WGS of Korean Idiopathic Bronchiectasis	nan	UNKNOWN
Thermal Spa Treatment and Improvement of Primary Ciliary Dyskinesia	nan	RECRUITING
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING
FA Clinical Outcome Measures	nan	ACTIVE_NOT_RECRUITING
Respiratory Registry for Lung Health: a Prospective, Observational Study on Adult Patients With Asthma or COPD	nan	UNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke	nan	COMPLETED
Clinical and Molecular Investigations Into Ciliopathies	nan	COMPLETED
Natural History of Asphyxiating Thoracic Dystrophy (DTJ)	nan	COMPLETED
Research of Therapeutic Targets in the Frame of Nephronophthisis and Renal Associated Ciliopathies	nan	RECRUITING
Clinical and Molecular Correlations in Spinocerebellar Ataxia Type 10 (SCA10)	nan	COMPLETED
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism	nan	COMPLETED
Gyrate Atrophy Ocular and Systemic Study	nan	ACTIVE_NOT_RECRUITING
Molecular Biomarkers Associated With Degenerative Joint Disease in the Knee	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CFAP410 binder may also engage these)

Protein	Name	Similarity
Q8C6G1	—	0.994	Q8C6G1 →
O75427	—	0.981	O75427 →
Q8K330	—	0.981	Q8K330 →
Q921G6	—	0.980	Q921G6 →
Q8WWN8	—	0.979	Q8WWN8 →
Q80XI6	—	0.979	Q80XI6 →
Q99ML2	—	0.979	Q99ML2 →
D3YY23	—	0.978	D3YY23 →
Q9D9B4	—	0.978	Q9D9B4 →
Q91ZJ0	—	0.978	Q91ZJ0 →
Q29RR1	—	0.978	Q29RR1 →
Q96P48	—	0.978	Q96P48 →
Q8CFK6	—	0.978	Q8CFK6 →
O75064	—	0.978	O75064 →
P58660	—	0.977	P58660 →
Q4R747	—	0.977	Q4R747 →
Q66HA1	—	0.977	Q66HA1 →
Q8C2S7	—	0.977	Q8C2S7 →
Q9BRR9	—	0.977	Q9BRR9 →
Q96FV0	—	0.977	Q96FV0 →
Q96I34	—	0.977	Q96I34 →
A0JPN4	—	0.976	A0JPN4 →
Q15345	—	0.976	Q15345 →
O43304	—	0.976	O43304 →
B5DFA1	—	0.976	B5DFA1 →
Q99KY4	—	0.976	Q99KY4 →
Q8BY98	—	0.976	Q8BY98 →
Q9Y6S9	—	0.976	Q9Y6S9 →
Q9Y4C4	—	0.976	Q9Y4C4 →
Q5XIS1	—	0.976	Q5XIS1 →