CHD1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL14844528	1.00	3/20
SCHEMBL25205454	1.00	3/20
SCHEMBL25228095	0.87	3/20
SCHEMBL25239433	0.87	3/20
SCHEMBL23682942	0.83	3/20
SCHEMBL23682930	0.81	3/20
SCHEMBL23682932	0.81	3/20
SCHEMBL18179252	0.80	3/20
SCHEMBL20525068	0.80	3/20
SCHEMBL19598912	0.80	3/20
SCHEMBL25198767	0.79	3/20
SCHEMBL25203229	0.78	3/20
SCHEMBL25239635	0.78	3/20
SCHEMBL23718000	0.74	3/20
SCHEMBL22265265	0.74	3/20
SCHEMBL16568970	0.73	3/20
SCHEMBL20303897	0.72	3/20
SCHEMBL20351018	0.72	3/20
Formic Acid (SCHEMBL20336820)	0.67	3/20
SCHEMBL20720595	0.67	3/20

Clinical trials — most relevant to CHD1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment	PHASE2/PHASE3	RECRUITING
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients	PHASE3	UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma	PHASE1/PHASE2	COMPLETED
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab	PHASE1/PHASE2	RECRUITING
Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors	PHASE1	COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load	PHASE1	COMPLETED
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma	PHASE1	UNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients	nan	RECRUITING
Global Profiling of Gene and Protein Expression Associated With Coronary Heart Disease Reversal	nan	COMPLETED
Genetics of Congenital Heart Disease	nan	RECRUITING
Accelerated Aging in Newborns and Adults With Congenital Heart Disease	nan	UNKNOWN
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions	nan	RECRUITING
UTHealth Turner Syndrome Research Registry	nan	RECRUITING
X-chromosome Inactivation, Epigenetics and the Transcriptome	nan	COMPLETED
Research for Genetic Factors Involved in Congenital Dislocation of Hip: Genome-wide Association Study in Grand West France	nan	COMPLETED
Clinical and Molecular Study of CHARGE Syndrom	nan	COMPLETED
CMOP Regimen and Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma	nan	UNKNOWN
dbGaP Protocol: The Pediatric Cardiac Genetics Consortium (PCGC)	nan	COMPLETED
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia	nan	COMPLETED
Antenatal Investigation of Fetuses With Complex Congenital Heart Defects Using multiOMICS	nan	RECRUITING
Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study	nan	RECRUITING
DNA Methylation and Autoimmune Thyroid Diseases	nan	COMPLETED
Chromosomal Abnormalities in Patients With Congenital Heart Disease at Assiut University Children's Hospital	nan	NOT_YET_RECRUITING
Genetic Markers of Coronary Heart Disease in Type 2 Diabetes	nan	COMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins	nan	COMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN
Genetic of SportS Induced Endofibrotic Remodeling	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CHD1 binder may also engage these)

Protein	Name	Similarity
B6ZLK2	—	1.000	B6ZLK2 →
P40201	—	1.000	P40201 →
E9PZM4	—	1.000	E9PZM4 →
O14647	—	1.000	O14647 →
D3ZA12	—	1.000	D3ZA12 →
A3KFM7	—	1.000	A3KFM7 →
Q8TD26	—	0.999	Q8TD26 →
Q7G8Y3	—	0.996	Q7G8Y3 →
Q04692	—	0.996	Q04692 →
B0R061	—	0.996	B0R061 →
Q8RWY3	—	0.995	Q8RWY3 →
B5VE38	—	0.995	B5VE38 →
F4JY24	—	0.995	F4JY24 →
Q7KU24	—	0.995	Q7KU24 →
Q7ZU90	—	0.994	Q7ZU90 →
O14139	—	0.994	O14139 →
Q9S775	—	0.994	Q9S775 →
Q9Y4B4	—	0.993	Q9Y4B4 →
E1B7X9	—	0.993	E1B7X9 →
D3Z9Z9	—	0.993	D3Z9Z9 →
P32657	—	0.993	P32657 →
C7GQI8	—	0.993	C7GQI8 →
O16102	—	0.993	O16102 →
A5E3K3	—	0.993	A5E3K3 →
P34739	—	0.992	P34739 →
Q9H4L7	—	0.992	Q9H4L7 →
A6ZL17	—	0.992	A6ZL17 →
Q9US25	—	0.992	Q9US25 →
O74393	—	0.992	O74393 →
Q9H1H9	—	0.992	Q9H1H9 →